Pharmacokinetic Profiles of Active Ingredients and Its Metabolites Derived from Rikkunshito, a Ghrelin Enhancer, in Healthy Japanese Volunteers: A Cross-Over, Randomized Study

• Hiroyuki Kitagawa,

  Affiliation Department of Surgery, Kochi Medical School, Kochi University, Kochi, Japan

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• Masaya Munekage,

  Affiliation Department of Surgery, Kochi Medical School, Kochi University, Kochi, Japan

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• Takashi Matsumoto ,

  * E-mail: matsumoto_takashi@mail.tsumura.co.jp

  Affiliation Tsumura Research Laboratories, Kampo Scientific Strategies Division, Tsumura & Co., Ibaraki, Japan

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• Chiharu Sadakane,

  Affiliation Tsumura Research Laboratories, Kampo Scientific Strategies Division, Tsumura & Co., Ibaraki, Japan

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• Miwako Fukutake,

  Affiliation Tsumura Research Laboratories, Kampo Scientific Strategies Division, Tsumura & Co., Ibaraki, Japan

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• Katsuyuki Aoki,

  Affiliation Kampo Formulations Development Center, Production Division, Tsumura & Co., Ibaraki, Japan

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• Junko Watanabe,

  Affiliation Tsumura Research Laboratories, Kampo Scientific Strategies Division, Tsumura & Co., Ibaraki, Japan

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• Kazuya Maemura,

  Affiliation Tsumura Research Laboratories, Kampo Scientific Strategies Division, Tsumura & Co., Ibaraki, Japan

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• Tomohisa Hattori,

  Affiliation Tsumura Research Laboratories, Kampo Scientific Strategies Division, Tsumura & Co., Ibaraki, Japan

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• Yosio Kase,

  Affiliation Tsumura Research Laboratories, Kampo Scientific Strategies Division, Tsumura & Co., Ibaraki, Japan

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• Yasuhito Uezono,

  Affiliation Division of Cancer Pathophysiology, National Cancer Center Research Institute, Tokyo, Japan

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• Akio Inui,

  Affiliation Department of Psychosomatic Internal Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan

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• Kazuhiro Hanazaki

  Affiliation Department of Surgery, Kochi Medical School, Kochi University, Kochi, Japan

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