Lack of Acid Sphingomyelinase Induces Age-Related Retinal Degeneration

Open Access

Peer-reviewed

Research Article

Bill X. Wu,

Affiliation Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina, United States of America
⨯
Jie Fan ,

* E-mail: fan@musc.edu

Affiliation Department of Ophthalmology, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, United States of America
⨯
Nicholas P. Boyer,

Affiliation Department of Ophthalmology, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, United States of America
⨯
Russell W. Jenkins,

Affiliation Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina, United States of America
⨯
Yiannis Koutalos,

Affiliation Department of Ophthalmology, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, United States of America
⨯
Yusuf A. Hannun,

Affiliations Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina, United States of America, Stony Brook Cancer Center and Department of Medicine, Stony Brook University, 100 Nicolls Rd., Stony Brook, New York, United States of America
⨯
Craig E. Crosson

Affiliation Department of Ophthalmology, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, United States of America
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Retinal degeneration
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Retina
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Lysosomes
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Sphingolipids
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Autophagic cell death
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Photoreceptors
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Genetically modified animals
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Lipids
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