Evidence that Chemical Chaperone 4-Phenylbutyric Acid Binds to Human Serum Albumin at Fatty Acid Binding Sites

Debasish Roy; Vinod Kumar; Joel James; Mohamed Sham Shihabudeen; Shweta Kulshrestha; Varun Goel; Kavitha Thirumurugan

doi:10.1371/journal.pone.0133012

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Peer-reviewed

Research Article

Evidence that Chemical Chaperone 4-Phenylbutyric Acid Binds to Human Serum Albumin at Fatty Acid Binding Sites

Debasish Roy ,

Contributed equally to this work with: Debasish Roy, Vinod Kumar

Affiliation 206, Structural Biology Lab, Center for Biomedical Research, Division of Biomedical Sciences, School of Bio Sciences and Technology, VIT University, Vellore-632014, Tamil Nadu, India
⨯
Vinod Kumar ,

Contributed equally to this work with: Debasish Roy, Vinod Kumar

Affiliation 206, Structural Biology Lab, Center for Biomedical Research, Division of Biomedical Sciences, School of Bio Sciences and Technology, VIT University, Vellore-632014, Tamil Nadu, India
⨯
Joel James,

Affiliation 206, Structural Biology Lab, Center for Biomedical Research, Division of Biomedical Sciences, School of Bio Sciences and Technology, VIT University, Vellore-632014, Tamil Nadu, India
⨯
Mohamed Sham Shihabudeen,

Affiliation 206, Structural Biology Lab, Center for Biomedical Research, Division of Biomedical Sciences, School of Bio Sciences and Technology, VIT University, Vellore-632014, Tamil Nadu, India
⨯
Shweta Kulshrestha,

Affiliation 206, Structural Biology Lab, Center for Biomedical Research, Division of Biomedical Sciences, School of Bio Sciences and Technology, VIT University, Vellore-632014, Tamil Nadu, India
⨯
Varun Goel,

Affiliation 206, Structural Biology Lab, Center for Biomedical Research, Division of Biomedical Sciences, School of Bio Sciences and Technology, VIT University, Vellore-632014, Tamil Nadu, India
⨯
Kavitha Thirumurugan

* E-mail: m.kavitha@vit.ac.in

Affiliation 206, Structural Biology Lab, Center for Biomedical Research, Division of Biomedical Sciences, School of Bio Sciences and Technology, VIT University, Vellore-632014, Tamil Nadu, India
⨯

Evidence that Chemical Chaperone 4-Phenylbutyric Acid Binds to Human Serum Albumin at Fatty Acid Binding Sites

Debasish Roy,
Vinod Kumar,
Joel James,
Mohamed Sham Shihabudeen,
Shweta Kulshrestha,
Varun Goel,
Kavitha Thirumurugan

Published: July 16, 2015
https://doi.org/10.1371/journal.pone.0133012

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