Whole Genome Sequencing Shows a Low Proportion of Tuberculosis Disease Is Attributable to Known Close Contacts in Rural Malawi

Judith R. Glynn; José Afonso Guerra-Assunção; Rein M. G. J. Houben; Lifted Sichali; Themba Mzembe; Lorrain K. Mwaungulu; J. Nimrod Mwaungulu; Ruth McNerney; Palwasha Khan; Julian Parkhill; Amelia C. Crampin; Taane G. Clark

doi:10.1371/journal.pone.0132840

Loading metrics

Open Access

Peer-reviewed

Research Article

Whole Genome Sequencing Shows a Low Proportion of Tuberculosis Disease Is Attributable to Known Close Contacts in Rural Malawi

Judith R. Glynn ,

* E-mail: Judith.glynn@lshtm.ac.uk

Affiliation Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, United Kingdom
⨯
José Afonso Guerra-Assunção,

Affiliation Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, United Kingdom
⨯
Rein M. G. J. Houben,

Affiliation Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, United Kingdom
⨯
Lifted Sichali,

Affiliation Karonga Prevention Study, Chilumba, Malawi
⨯
Themba Mzembe,

Affiliation Karonga Prevention Study, Chilumba, Malawi
⨯
Lorrain K. Mwaungulu,

Affiliation Karonga Prevention Study, Chilumba, Malawi
⨯
J. Nimrod Mwaungulu,

Affiliation Karonga Prevention Study, Chilumba, Malawi
⨯
Ruth McNerney,

Affiliation Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom
⨯
Palwasha Khan,

Affiliation Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, United Kingdom
⨯
Julian Parkhill,

Affiliation Wellcome Trust Sanger Institute, Hinxton, United Kingdom
⨯
Amelia C. Crampin,

Affiliations Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, United Kingdom, Karonga Prevention Study, Chilumba, Malawi
⨯
Taane G. Clark

Affiliations Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, United Kingdom, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom
⨯

Whole Genome Sequencing Shows a Low Proportion of Tuberculosis Disease Is Attributable to Known Close Contacts in Rural Malawi

Judith R. Glynn,
José Afonso Guerra-Assunção,
Rein M. G. J. Houben,
Lifted Sichali,
Themba Mzembe,
Lorrain K. Mwaungulu,
J. Nimrod Mwaungulu,
Ruth McNerney,
Palwasha Khan,
Julian Parkhill

Published: July 16, 2015
https://doi.org/10.1371/journal.pone.0132840

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Tuberculosis
Is the Subject Area "Tuberculosis" applicable to this article?

Thanks for your feedback.
Single nucleotide polymorphisms
Is the Subject Area "Single nucleotide polymorphisms" applicable to this article?

Thanks for your feedback.
HIV
Is the Subject Area "HIV" applicable to this article?

Thanks for your feedback.
Genomics
Is the Subject Area "Genomics" applicable to this article?

Thanks for your feedback.
Medical risk factors
Is the Subject Area "Medical risk factors" applicable to this article?

Thanks for your feedback.
Genome sequencing
Is the Subject Area "Genome sequencing" applicable to this article?

Thanks for your feedback.
Genetic fingerprinting
Is the Subject Area "Genetic fingerprinting" applicable to this article?

Thanks for your feedback.
Malawi
Is the Subject Area "Malawi" applicable to this article?

Thanks for your feedback.