Identification of Two Novel HOXB13 Germline Mutations in Portuguese Prostate Cancer Patients

Sofia Maia; Marta Cardoso; Pedro Pinto; Manuela Pinheiro; Catarina Santos; Ana Peixoto; Maria José Bento; Jorge Oliveira; Rui Henrique; Carmen Jerónimo; Manuel R. Teixeira

doi:10.1371/journal.pone.0132728

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Open Access

Peer-reviewed

Research Article

Identification of Two Novel HOXB13 Germline Mutations in Portuguese Prostate Cancer Patients

Sofia Maia,

Affiliation Department of Genetics and Cancer Genetics Group–CI-IPOP, Portuguese Oncology Institute–Porto, Porto, Portugal
⨯
Marta Cardoso,

Affiliation Department of Genetics and Cancer Genetics Group–CI-IPOP, Portuguese Oncology Institute–Porto, Porto, Portugal
⨯
Pedro Pinto,

Affiliation Department of Genetics and Cancer Genetics Group–CI-IPOP, Portuguese Oncology Institute–Porto, Porto, Portugal
⨯
Manuela Pinheiro,

Affiliation Department of Genetics and Cancer Genetics Group–CI-IPOP, Portuguese Oncology Institute–Porto, Porto, Portugal
⨯
Catarina Santos,

Affiliation Department of Genetics and Cancer Genetics Group–CI-IPOP, Portuguese Oncology Institute–Porto, Porto, Portugal
⨯
Ana Peixoto,

Affiliation Department of Genetics and Cancer Genetics Group–CI-IPOP, Portuguese Oncology Institute–Porto, Porto, Portugal
⨯
Maria José Bento,

Affiliations Department of Epidemiology, Portuguese Oncology Institute–Porto, Porto, Portugal, North Region Cancer Registry, Portuguese Oncology Institute–Porto, Porto, Portugal, Biomedical Sciences Institute (ICBAS), University of Porto–Porto, Portugal
⨯
Jorge Oliveira,

Affiliation Department of Urology, Portuguese Oncology Institute–Porto, Porto, Portugal
⨯
Rui Henrique,

Affiliations Biomedical Sciences Institute (ICBAS), University of Porto–Porto, Portugal, Cancer Biology and Epigenetics Group–CI-IPOP, Portuguese Oncology Institute–Porto, Porto, Portugal, Department of Pathology, Portuguese Oncology Institute–Porto, Porto, Portugal
⨯
Carmen Jerónimo,

Affiliations Biomedical Sciences Institute (ICBAS), University of Porto–Porto, Portugal, Cancer Biology and Epigenetics Group–CI-IPOP, Portuguese Oncology Institute–Porto, Porto, Portugal
⨯
Manuel R. Teixeira

* E-mail: manuel.teixeira@ipoporto.min-saude.pt

Affiliations Department of Genetics and Cancer Genetics Group–CI-IPOP, Portuguese Oncology Institute–Porto, Porto, Portugal, Biomedical Sciences Institute (ICBAS), University of Porto–Porto, Portugal
⨯

Identification of Two Novel HOXB13 Germline Mutations in Portuguese Prostate Cancer Patients

Sofia Maia,
Marta Cardoso,
Pedro Pinto,
Manuela Pinheiro,
Catarina Santos,
Ana Peixoto,
Maria José Bento,
Jorge Oliveira,
Rui Henrique,
Carmen Jerónimo

Published: July 15, 2015
https://doi.org/10.1371/journal.pone.0132728

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Prostate cancer
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Cancer detection and diagnosis
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Breast cancer
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Homeobox
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Germline mutation
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