Tacrolimus Protects Podocytes from Injury in Lupus Nephritis Partly by Stabilizing the Cytoskeleton and Inhibiting Podocyte Apoptosis

Ruyi Liao; Qinghua Liu; Zhihua Zheng; Jinjin Fan; Wenxing Peng; Qingyu Kong; Huijuan He; Shicong Yang; Wenfang Chen; Xueqing Tang; Xueqing Yu

doi:10.1371/journal.pone.0132724

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Open Access

Peer-reviewed

Research Article

Tacrolimus Protects Podocytes from Injury in Lupus Nephritis Partly by Stabilizing the Cytoskeleton and Inhibiting Podocyte Apoptosis

Ruyi Liao ,

Contributed equally to this work with: Ruyi Liao, Qinghua Liu

Affiliations Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Guangdong Provincial Key Laboratory of Nephrology, Guangzhou, China, Key Laboratory of Nephrology, Ministry of Health, Guangzhou, China
⨯
Qinghua Liu ,

Contributed equally to this work with: Ruyi Liao, Qinghua Liu

Affiliations Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Guangdong Provincial Key Laboratory of Nephrology, Guangzhou, China, Key Laboratory of Nephrology, Ministry of Health, Guangzhou, China
⨯
Zhihua Zheng,

Affiliations Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Guangdong Provincial Key Laboratory of Nephrology, Guangzhou, China, Key Laboratory of Nephrology, Ministry of Health, Guangzhou, China
⨯
Jinjin Fan,

Affiliations Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Guangdong Provincial Key Laboratory of Nephrology, Guangzhou, China, Key Laboratory of Nephrology, Ministry of Health, Guangzhou, China
⨯
Wenxing Peng,

Affiliations Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Guangdong Provincial Key Laboratory of Nephrology, Guangzhou, China, Key Laboratory of Nephrology, Ministry of Health, Guangzhou, China
⨯
Qingyu Kong,

Affiliations Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Guangdong Provincial Key Laboratory of Nephrology, Guangzhou, China, Key Laboratory of Nephrology, Ministry of Health, Guangzhou, China
⨯
Huijuan He,

Affiliations Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Guangdong Provincial Key Laboratory of Nephrology, Guangzhou, China, Key Laboratory of Nephrology, Ministry of Health, Guangzhou, China
⨯
Shicong Yang,

Affiliation Department of Pathology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
⨯
Wenfang Chen,

Affiliation Department of Pathology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
⨯
Xueqing Tang,

Affiliations Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Guangdong Provincial Key Laboratory of Nephrology, Guangzhou, China, Key Laboratory of Nephrology, Ministry of Health, Guangzhou, China
⨯
Xueqing Yu

* E-mail: yuxq@mail.sysu.edu.cn

Affiliations Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Guangdong Provincial Key Laboratory of Nephrology, Guangzhou, China, Key Laboratory of Nephrology, Ministry of Health, Guangzhou, China
⨯

Tacrolimus Protects Podocytes from Injury in Lupus Nephritis Partly by Stabilizing the Cytoskeleton and Inhibiting Podocyte Apoptosis

Ruyi Liao,
Qinghua Liu,
Zhihua Zheng,
Jinjin Fan,
Wenxing Peng,
Qingyu Kong,
Huijuan He,
Shicong Yang,
Wenfang Chen,
Xueqing Tang

Published: July 10, 2015
https://doi.org/10.1371/journal.pone.0132724

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