Analysis of DNA Double-Strand Breaks and Cytotoxicity after 7 Tesla Magnetic Resonance Imaging of Isolated Human Lymphocytes

Annika Reddig; Mahsa Fatahi; Björn Friebe; Karina Guttek; Roland Hartig; Frank Godenschweger; Dirk Roggenbuck; Jens Ricke; Dirk Reinhold; Oliver Speck

doi:10.1371/journal.pone.0132702

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Open Access

Peer-reviewed

Research Article

Analysis of DNA Double-Strand Breaks and Cytotoxicity after 7 Tesla Magnetic Resonance Imaging of Isolated Human Lymphocytes

Annika Reddig ,

Contributed equally to this work with: Annika Reddig, Mahsa Fatahi, Björn Friebe

* E-mail: annika.reddig@med.ovgu.de

Affiliation Institute of Molecular and Clinical Immunology, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany
⨯
Mahsa Fatahi ,

Contributed equally to this work with: Annika Reddig, Mahsa Fatahi, Björn Friebe

Affiliation Department of Biomedical Magnetic Resonance, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany
⨯
Björn Friebe ,

Contributed equally to this work with: Annika Reddig, Mahsa Fatahi, Björn Friebe

Affiliation Department of Radiology and Nuclear Medicine, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany
⨯
Karina Guttek,

Affiliation Institute of Molecular and Clinical Immunology, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany
⨯
Roland Hartig,

Affiliation Institute of Molecular and Clinical Immunology, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany
⨯
Frank Godenschweger,

Affiliation Department of Biomedical Magnetic Resonance, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany
⨯
Dirk Roggenbuck,

Affiliations Medipan GmbH, Dahlewitz/Berlin, Germany, Faculty of Natural Sciences, Brandenburg University of Technology Cottbus-Senftenberg, Senftenberg, Germany
⨯
Jens Ricke,

Affiliation Department of Radiology and Nuclear Medicine, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany
⨯
Dirk Reinhold ,

¶‡ These authors also contributed equally to this work and shared senior authorship.

Affiliation Institute of Molecular and Clinical Immunology, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany
⨯
Oliver Speck

¶‡ These authors also contributed equally to this work and shared senior authorship.

Affiliations Department of Biomedical Magnetic Resonance, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany, Leibniz Institute for Neurobiology, Magdeburg, Germany, Center for Behavioral Brain Sciences, Magdeburg, Germany, German Center for Neurodegenerative Disease, Magdeburg, Germany
⨯

Analysis of DNA Double-Strand Breaks and Cytotoxicity after 7 Tesla Magnetic Resonance Imaging of Isolated Human Lymphocytes

Annika Reddig,
Mahsa Fatahi,
Björn Friebe,
Karina Guttek,
Roland Hartig,
Frank Godenschweger,
Dirk Roggenbuck,
Jens Ricke,
Dirk Reinhold,
Oliver Speck

Published: July 15, 2015
https://doi.org/10.1371/journal.pone.0132702

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Magnetic resonance imaging
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Flow cytometry
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DNA damage
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Ionizing radiation
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Lymphocytes
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Cell staining
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Cytotoxicity
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