Energy Metabolism Disorder as a Contributing Factor of Rheumatoid Arthritis: A Comparative Proteomic and Metabolomic Study

Xin Yu Yang; Kai Di Zheng; Ke Lin; Guifeng Zheng; Hai Zou; Jian Min Wang; Yao Yao Lin; Chifundo Martha Chuka; Ren Shan Ge; Weitao Zhai; Jian Guang Wang

doi:10.1371/journal.pone.0132695

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Open Access

Peer-reviewed

Research Article

Energy Metabolism Disorder as a Contributing Factor of Rheumatoid Arthritis: A Comparative Proteomic and Metabolomic Study

Xin Yu Yang ,

Contributed equally to this work with: Xin Yu Yang, Kai Di Zheng, Ke Lin

Affiliation Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China
⨯
Kai Di Zheng ,

Contributed equally to this work with: Xin Yu Yang, Kai Di Zheng, Ke Lin

Affiliation Department of Biochemistry, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China
⨯
Ke Lin ,

Contributed equally to this work with: Xin Yu Yang, Kai Di Zheng, Ke Lin

Affiliation Department of Biochemistry, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China
⨯
Guifeng Zheng,

Affiliation Department of Biochemistry, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China
⨯
Hai Zou,

Affiliation Department of Biochemistry, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China
⨯
Jian Min Wang,

Affiliation Department of Rheumatology, Jiamusi Central Hospital, Jiamusi, China
⨯
Yao Yao Lin,

Affiliation Department of Biochemistry, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China
⨯
Chifundo Martha Chuka,

Affiliation Department of Biochemistry, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China
⨯
Ren Shan Ge,

Affiliation Department of Biochemistry, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China
⨯
Weitao Zhai ,

* E-mail: wz_wjg@163.com for (JGW); wtzhai@yahoo.com.cn for (WZ)

Affiliation Department of Orthopaedic Surgery, Shanghai Guanghua Special Hospital for Rheumatoid Arthritis, Shanghai, China
⨯
Jian Guang Wang

* E-mail: wz_wjg@163.com for (JGW); wtzhai@yahoo.com.cn for (WZ)

Affiliation Department of Biochemistry, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China
⨯

Energy Metabolism Disorder as a Contributing Factor of Rheumatoid Arthritis: A Comparative Proteomic and Metabolomic Study

Xin Yu Yang,
Kai Di Zheng,
Ke Lin,
Guifeng Zheng,
Hai Zou,
Jian Min Wang,
Yao Yao Lin,
Chifundo Martha Chuka,
Ren Shan Ge,
Weitao Zhai

Published: July 6, 2015
https://doi.org/10.1371/journal.pone.0132695

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Rheumatoid arthritis
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Synovial fluid
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Enzyme metabolism
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Energy metabolism
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