Mutational Dissection of Telomeric DNA Binding Requirements of G4 Resolvase 1 Shows that G4-Structure and Certain 3’-Tail Sequences Are Sufficient for Tight and Complete Binding

• Philip J. Smaldino,

  Affiliation Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, North Carolina, 27157, United States of America

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• Eric D. Routh,

  Affiliation Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, North Carolina, 27157, United States of America

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• Jung H. Kim,

  Affiliation Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, North Carolina, 27157, United States of America

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• Banabihari Giri,

  Affiliation Department of Chemistry, Furman University, Greenville, South Carolina, 29613, United States of America

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• Steven D. Creacy,

  Affiliations Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, North Carolina, 27157, United States of America, Harmonyx Diagnostics, Cordova, Tennessee, 38016, United States of America

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• Roy R. Hantgan,

  Affiliation Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, North Carolina, 27157, United States of America

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• Steven A. Akman,

  Affiliation Department of Hematology and Oncology, Roper St. Francis Hospital, Charleston, South Carolina, 29401, United States of America

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• James P. Vaughn

  * E-mail: jpvaughn@nanomedica.com

  Affiliation Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, North Carolina, 27157, United States of America

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