Quantitative Influence of ABO Blood Groups on Factor VIII and Its Ratio to von Willebrand Factor, Novel Observations from an ARIC Study of 11,673 Subjects

Jaewoo Song; Fengju Chen; Marco Campos; Doug Bolgiano; Katie Houck; Lloyd E. Chambless; Kenneth K. Wu; Aaron R. Folsom; David Couper; Eric Boerwinkle; Jing-fei Dong

doi:10.1371/journal.pone.0132626

Loading metrics

Open Access

Peer-reviewed

Research Article

Quantitative Influence of ABO Blood Groups on Factor VIII and Its Ratio to von Willebrand Factor, Novel Observations from an ARIC Study of 11,673 Subjects

Jaewoo Song ,

Contributed equally to this work with: Jaewoo Song, Fengju Chen

Affiliations Puget Sound Blood Center Research Institute, Puget Sound Blood Center, Seattle, Washington, United States of America, Department of Laboratory Medicine, Yonsei University, College of Medicine, Seoul, Korea
⨯
Fengju Chen ,

Contributed equally to this work with: Jaewoo Song, Fengju Chen

Affiliation Human Genetic Center, University of Texas School of Public Health, Houston, Texas, United States of America
⨯
Marco Campos,

Affiliation Cardiology Section, Department of Medicine, Baylor College of Medicine, Houston, Texas, United States of America
⨯
Doug Bolgiano,

Affiliation Puget Sound Blood Center Research Institute, Puget Sound Blood Center, Seattle, Washington, United States of America
⨯
Katie Houck,

Affiliation Puget Sound Blood Center Research Institute, Puget Sound Blood Center, Seattle, Washington, United States of America
⨯
Lloyd E. Chambless,

Affiliation Department of Biostatistics, University of North Carolina, Chapel Hill, North Carolina, United States of America
⨯
Kenneth K. Wu,

Affiliation National Health Research Institutes, Taipei, Taiwan
⨯
Aaron R. Folsom,

Affiliation Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, United States of America
⨯
David Couper,

Affiliation Department of Biostatistics, University of North Carolina, Chapel Hill, North Carolina, United States of America
⨯
Eric Boerwinkle,

Affiliation Human Genetic Center, University of Texas School of Public Health, Houston, Texas, United States of America
⨯
Jing-fei Dong

* E-mail: jfdong@psbc.org

Affiliations Puget Sound Blood Center Research Institute, Puget Sound Blood Center, Seattle, Washington, United States of America, Division of Hematology, Department of Medicine, University of Washington, School of Medicine, Seattle, Washington, United States of America
⨯

Quantitative Influence of ABO Blood Groups on Factor VIII and Its Ratio to von Willebrand Factor, Novel Observations from an ARIC Study of 11,673 Subjects

Jaewoo Song,
Fengju Chen,
Marco Campos,
Doug Bolgiano,
Katie Houck,
Lloyd E. Chambless,
Kenneth K. Wu,
Aaron R. Folsom,
David Couper,
Eric Boerwinkle

Published: August 5, 2015
https://doi.org/10.1371/journal.pone.0132626

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Blood groups
Is the Subject Area "Blood groups" applicable to this article?

Thanks for your feedback.
Diabetes mellitus
Is the Subject Area "Diabetes mellitus" applicable to this article?

Thanks for your feedback.
Blood plasma
Is the Subject Area "Blood plasma" applicable to this article?

Thanks for your feedback.
Single nucleotide polymorphisms
Is the Subject Area "Single nucleotide polymorphisms" applicable to this article?

Thanks for your feedback.
Blood
Is the Subject Area "Blood" applicable to this article?

Thanks for your feedback.
Atherosclerosis
Is the Subject Area "Atherosclerosis" applicable to this article?

Thanks for your feedback.
Variant genotypes
Is the Subject Area "Variant genotypes" applicable to this article?

Thanks for your feedback.
Coagulation factors
Is the Subject Area "Coagulation factors" applicable to this article?

Thanks for your feedback.