Targeting of Topoisomerase I for Prognoses and Therapeutics of Camptothecin-Resistant Ovarian Cancer

Yu-Chieh Lee; Chii-Hong Lee; Hsiang-Ping Tsai; Herng-Wei An; Chi-Ming Lee; Jen-Chine Wu; Chien-Shu Chen; Shih-Hao Huang; Jaulang Hwang; Kur-Ta Cheng; Phui-Ly Leiw; Chi-Long Chen; Chun-Mao Lin

doi:10.1371/journal.pone.0132579

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Open Access

Peer-reviewed

Research Article

Targeting of Topoisomerase I for Prognoses and Therapeutics of Camptothecin-Resistant Ovarian Cancer

Yu-Chieh Lee ,

Contributed equally to this work with: Yu-Chieh Lee, Chii-Hong Lee

Affiliation Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan
⨯
Chii-Hong Lee ,

Contributed equally to this work with: Yu-Chieh Lee, Chii-Hong Lee

Affiliation Department of Pathology, Taipei Medical University-Shuang Ho Hospital, New Taipei City, Taiwan
⨯
Hsiang-Ping Tsai,

Affiliation Department of Biochemistry, School of Medicine, Taipei Medical University, Taipei, Taiwan
⨯
Herng-Wei An,

Affiliation Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan
⨯
Chi-Ming Lee,

Affiliation Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan
⨯
Jen-Chine Wu,

Affiliation Center for Stem Cells and Translational Cancer Research, Chang Gung Memorial Hospital, Gueishan, Taoyuan County, Taiwan
⨯
Chien-Shu Chen,

Affiliation School of Pharmacy, China Medical University, Taichung, Taiwan
⨯
Shih-Hao Huang,

Affiliation Department of Food and Beverage Management, Taipei College of Maritime Technology, Taipei, Taiwan
⨯
Jaulang Hwang,

Affiliation Department of Biochemistry, School of Medicine, Taipei Medical University, Taipei, Taiwan
⨯
Kur-Ta Cheng,

Affiliation Department of Biochemistry, School of Medicine, Taipei Medical University, Taipei, Taiwan
⨯
Phui-Ly Leiw,

Affiliation Department of Pathology, Taipei Medical University-Shuang Ho Hospital, New Taipei City, Taiwan
⨯
Chi-Long Chen,

Affiliations Department of Pathology, College of Medicine, Taipei Medical University, Taipei, Taiwan, Department of Pathology, Taipei Medical University Hospital, Taipei, Taiwan
⨯
Chun-Mao Lin

* E-mail: cmlin@tmu.edu.tw

Affiliation Department of Biochemistry, School of Medicine, Taipei Medical University, Taipei, Taiwan
⨯

Targeting of Topoisomerase I for Prognoses and Therapeutics of Camptothecin-Resistant Ovarian Cancer

Yu-Chieh Lee,
Chii-Hong Lee,
Hsiang-Ping Tsai,
Herng-Wei An,
Chi-Ming Lee,
Jen-Chine Wu,
Chien-Shu Chen,
Shih-Hao Huang,
Jaulang Hwang,
Kur-Ta Cheng

Published: July 24, 2015
https://doi.org/10.1371/journal.pone.0132579

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