Inhibition of Calcium Influx Reduces Dysfunction and Apoptosis in Lipotoxic Pancreatic β-Cells via Regulation of Endoplasmic Reticulum Stress

Open Access

Peer-reviewed

Research Article

Yuren Zhou ,

Contributed equally to this work with: Yuren Zhou, Peng Sun

Affiliation Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai, 201203, China
⨯
Peng Sun ,

Contributed equally to this work with: Yuren Zhou, Peng Sun

Affiliations Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai, 201203, China, School of Pharmacy, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai, 201203, China
⨯
Ting Wang,

Affiliation Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai, 201203, China
⨯
Kaixian Chen,

Affiliations Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai, 201203, China, School of Pharmacy, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai, 201203, China
⨯
Weiliang Zhu,

Affiliation Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai, 201203, China
⨯
Heyao Wang

* E-mail: hywang@simm.ac.cn

Affiliation Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai, 201203, China
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Diazo compounds
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Apoptosis
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Insulin secretion
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Phosphorylation
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Glucose
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Cell staining
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Endoplasmic reticulum
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MAPK signaling cascades
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