EpCAM Aptamer-siRNA Chimera Targets and Regress Epithelial Cancer

Nithya Subramanian; Jagat R. Kanwar; Rupinder K. Kanwar; JagadeeshBabu Sreemanthula; Jyotirmay Biswas; Vikas Khetan; Subramanian Krishnakumar

doi:10.1371/journal.pone.0132407

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Open Access

Peer-reviewed

Research Article

EpCAM Aptamer-siRNA Chimera Targets and Regress Epithelial Cancer

Nithya Subramanian,

Affiliations Department of Nanobiotechnology, Vision Research Foundation, Kamalnayan Bajaj Institute for Research in Vision and Ophthalmology, Chennai, India, Nanomedicine-Laboratory of Immunology and Molecular Biomedical Research (NLIMBR), School of Medicine (SoM), Centre for Molecular and Medical Research (C-MMR), Faculty of Health, Deakin University, Geelong, Victoria-3217, Australia
⨯
Jagat R. Kanwar ,

* E-mail: drkrishnakumar_2000@yahoo.com (SK); jagat.kanwar@deakin.edu.au (JK)

Affiliation Nanomedicine-Laboratory of Immunology and Molecular Biomedical Research (NLIMBR), School of Medicine (SoM), Centre for Molecular and Medical Research (C-MMR), Faculty of Health, Deakin University, Geelong, Victoria-3217, Australia
⨯
Rupinder K. Kanwar,

Affiliation Nanomedicine-Laboratory of Immunology and Molecular Biomedical Research (NLIMBR), School of Medicine (SoM), Centre for Molecular and Medical Research (C-MMR), Faculty of Health, Deakin University, Geelong, Victoria-3217, Australia
⨯
JagadeeshBabu Sreemanthula,

Affiliation L & T Ocular Pathology department, Vision Research Foundation, Kamalnayan Bajaj Institute for Research in Vision and Ophthalmology, Chennai, India
⨯
Jyotirmay Biswas,

Affiliation L & T Ocular Pathology department, Vision Research Foundation, Kamalnayan Bajaj Institute for Research in Vision and Ophthalmology, Chennai, India
⨯
Vikas Khetan,

Affiliation Department of Ocular Oncology and Vitreoretina, Medical Research Foundation, Sankara Nethralaya, Chennai, India
⨯
Subramanian Krishnakumar

* E-mail: drkrishnakumar_2000@yahoo.com (SK); jagat.kanwar@deakin.edu.au (JK)

Affiliations Department of Nanobiotechnology, Vision Research Foundation, Kamalnayan Bajaj Institute for Research in Vision and Ophthalmology, Chennai, India, L & T Ocular Pathology department, Vision Research Foundation, Kamalnayan Bajaj Institute for Research in Vision and Ophthalmology, Chennai, India
⨯

EpCAM Aptamer-siRNA Chimera Targets and Regress Epithelial Cancer

Nithya Subramanian,
Jagat R. Kanwar,
Rupinder K. Kanwar,
JagadeeshBabu Sreemanthula,
Jyotirmay Biswas,
Vikas Khetan,
Subramanian Krishnakumar

Published: July 15, 2015
https://doi.org/10.1371/journal.pone.0132407

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