Diffused Intra-Oocyte Hydrogen Peroxide Activates Myeloperoxidase and Deteriorates Oocyte Quality

Sana N. Khan; Faten Shaeib; Tohid Najafi; Mahendra Kavdia; Bernard Gonik; Ghassan M. Saed; Pravin T. Goud; Husam M. Abu-Soud

doi:10.1371/journal.pone.0132388

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Peer-reviewed

Research Article

Diffused Intra-Oocyte Hydrogen Peroxide Activates Myeloperoxidase and Deteriorates Oocyte Quality

Sana N. Khan,

Affiliation Department of Obstetrics and Gynecology, The C, S, Mott Center for Human Growth and Development, Wayne State University School of Medicine, Detroit Michigan, United States of America
⨯
Faten Shaeib,

Affiliation Department of Obstetrics and Gynecology, The C, S, Mott Center for Human Growth and Development, Wayne State University School of Medicine, Detroit Michigan, United States of America
⨯
Tohid Najafi,

Affiliations Department of Obstetrics and Gynecology, The C, S, Mott Center for Human Growth and Development, Wayne State University School of Medicine, Detroit Michigan, United States of America, Department of Biochemistry and Molecular Biology, Wayne State University School of Medicine, Detroit, Michigan, United States of America
⨯
Mahendra Kavdia,

Affiliation Department of Biomedical Engineering, Wayne State University, Detroit, Michigan, United States of America
⨯
Bernard Gonik,

Affiliation Department of Obstetrics and Gynecology, The C, S, Mott Center for Human Growth and Development, Wayne State University School of Medicine, Detroit Michigan, United States of America
⨯
Ghassan M. Saed,

Affiliation Department of Obstetrics and Gynecology, The C, S, Mott Center for Human Growth and Development, Wayne State University School of Medicine, Detroit Michigan, United States of America
⨯
Pravin T. Goud,

Affiliation Department of Obstetrics and gynecology, Division of Reproductive Endocrinology and Infertility, University of California Davis, Sacramento, California, United States of America, and California IVF Fertility Center, Davis and Sacramento, California, United States of America
⨯
Husam M. Abu-Soud

* E-mail: habusoud@med.wayne.edu

Affiliations Department of Obstetrics and Gynecology, The C, S, Mott Center for Human Growth and Development, Wayne State University School of Medicine, Detroit Michigan, United States of America, Department of Biochemistry and Molecular Biology, Wayne State University School of Medicine, Detroit, Michigan, United States of America
⨯

Diffused Intra-Oocyte Hydrogen Peroxide Activates Myeloperoxidase and Deteriorates Oocyte Quality

Sana N. Khan,
Faten Shaeib,
Tohid Najafi,
Mahendra Kavdia,
Bernard Gonik,
Ghassan M. Saed,
Pravin T. Goud,
Husam M. Abu-Soud

Published: July 21, 2015
https://doi.org/10.1371/journal.pone.0132388

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