Computational Modeling of a Transcriptional Switch Underlying B-Lymphocyte Lineage Commitment of Hematopoietic Multipotent Cells

Open Access

Peer-reviewed

Research Article

Luca Salerno ,

Contributed equally to this work with: Luca Salerno, Carlo Cosentino

Affiliation Laboratory of Biomechatronics, Department of Experimental and Clinical Medicine, University Magna Græcia of Catanzaro, Catanzaro, Italy
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Carlo Cosentino ,

Contributed equally to this work with: Luca Salerno, Carlo Cosentino

* E-mail: carlo.cosentino@unicz.it

Affiliation Laboratory of Biomechatronics, Department of Experimental and Clinical Medicine, University Magna Græcia of Catanzaro, Catanzaro, Italy
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Giovanni Morrone,

Affiliation Laboratory of Molecular Haematopoiesis and Stem Cell Biology, Department of Experimental and Clinical Medicine, University Magna Græcia of Catanzaro, Catanzaro, Italy
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Francesco Amato

Affiliation Laboratory of Biomechatronics, Department of Experimental and Clinical Medicine, University Magna Græcia of Catanzaro, Catanzaro, Italy
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B cells
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Multipotency
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Transcription factors
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Cell differentiation
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Gene expression
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Transcriptional control
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DNA transcription
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Mathematical models
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