The Topoisomerase 1 Inhibitor Austrobailignan-1 Isolated from Koelreuteria henryi Induces a G2/M-Phase Arrest and Cell Death Independently of p53 in Non-Small Cell Lung Cancer Cells

• Chun-Chi Wu ,

  Contributed equally to this work with: Chun-Chi Wu, Keh-Feng Huang

  Affiliations Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan, ROC, Department of Medical Research, Chung-Shan Medical University Hospital, Taichung, Taiwan, ROC

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• Keh-Feng Huang ,

  Contributed equally to this work with: Chun-Chi Wu, Keh-Feng Huang

  Affiliation Department of Applied Chemistry, Providence University, Taichung, Taiwan, ROC

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• Tsung-Ying Yang,

  Affiliations Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan, ROC, Department of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC

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• Ya-Ling Li,

  Affiliation Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan, ROC

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• Chi-Luan Wen,

  Affiliation Taiwan Seed Improvement and Propagation Station, Council of Agriculture, Propagation Technology Section, Taichung, Taiwan, ROC

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• Shih-Lan Hsu,

  Affiliation Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan, ROC

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• Tzu-Hsiu Chen

  * E-mail: hsiu@mail.cnu.edu.tw

  Affiliation Department of Health and Nutrition, Chia Nan University of Pharmacy & Science, Tainan, Taiwan, ROC

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