Excess Mortality in Patients with Multiple Sclerosis Starts at 20 Years from Clinical Onset: Data from a Large-Scale French Observational Study

• Emmanuelle Leray ,

  * E-mail: emmanuelle.leray@ehesp.fr

  Affiliation Department of Epidemiology, EHESP Rennes, Sorbonne Paris Cité; CIC-P 1414, CHU Rennes, West Neuroscience Network of Excellence (WENNE), Rennes, France

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• Sandra Vukusic,

  Affiliation Department of Neurology, CHU Lyon, Observatoire Français de la Sclérose En Plaques (OFSEP), Lyon, France

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• Marc Debouverie,

  Affiliation ReLSEP, Lorraine Register of MS, EA 4360, Department of Neurology, CHU Nancy, Nancy, France

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• Michel Clanet,

  Affiliation Department of Neurology, CHU Toulouse, Toulouse, France

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• Bruno Brochet,

  Affiliation Department of Neurology, CHU Bordeaux, Bordeaux, France

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• Jérôme de Sèze,

  Affiliation Department of Neurology, Hopitaux Universitaire de Strasbourg, Clinical investigation center (CIC INSERM 1434) and UMR INSERM 1119/Federation de Medecine translationnelle (FMTS), Strasbourg, France

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• Hélène Zéphir,

  Affiliation Université de Lille, Department of Neurology, Hôpital Roger Salengro, CHRU de Lille, Lille, France

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• Gilles Defer,

  Affiliation Department of Neurology, CHU Caen, Caen, France

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• Christine Lebrun-Frenay,

  Affiliation Department of Neurology, CHU Nice, Nice, France

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• Thibault Moreau,

  Affiliation Department of Neurology, CHU Dijon, Dijon, France

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• Pierre Clavelou,

  Affiliation Department of Neurology, CHU Clermont-Ferrand, Clermont-Ferrand, France

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• Jean Pelletier,

  Affiliation APHM, Hôpital de La Timone, Pôle de Neurosciences Cliniques, Department of Neurology, Marseille, France

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• Eric Berger,

  Affiliation Department of Neurology, CHU Besançon, Besançon, France

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• Philippe Cabre,

  Affiliation Department of Neurology, CHU de Martinique, Martinique, France

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• Jean-Philippe Camdessanché,

  Affiliation Department of Neurology, CHU Saint-Etienne, Saint-Etienne, France

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• Shoshannah Kalson-Ray,

  Affiliation Department of Epidemiology, EHESP Rennes, Sorbonne Paris Cité, Paris, France

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• Christian Confavreux,

  Affiliation Department of Neurology, CHU Lyon, Lyon, France

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•  [ ... ],
• Gilles Edan

  Affiliation Department of Neurology, CHU Rennes, WEst Neuroscience Network of Excellence (WENNE), Rennes, France

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