Inhibition of Thrombopoietin/Mpl Signaling in Adult Hematopoiesis Identifies New Candidates for Hematopoietic Stem Cell Maintenance

• Saskia Kohlscheen ,

  Contributed equally to this work with: Saskia Kohlscheen, Sabine Wintterle

  Affiliations Research Group for Gene Modification in Stem Cells, LOEWE Center for Cell and Gene Therapy Frankfurt/Main and the Paul-Ehrlich-Institute, Langen, Germany, Institute of Experimental Hematology; Hannover Medical School, Hannover, Germany

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• Sabine Wintterle ,

  Contributed equally to this work with: Saskia Kohlscheen, Sabine Wintterle

  Affiliation Institute of Experimental Hematology; Hannover Medical School, Hannover, Germany

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• Adrian Schwarzer,

  Affiliation Institute of Experimental Hematology; Hannover Medical School, Hannover, Germany

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• Christel Kamp,

  Affiliation Department of Biostatistik, Paul-Ehrlich-Institute, Langen, Germany

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• Martijn H. Brugman,

  Affiliation Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, ZA Leiden, The Netherlands

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• Daniel C. Breuer,

  Current Address: Hannover Clinical Trial Center (HCTC), Hannover, Germany

  Affiliation Institute of Experimental Hematology; Hannover Medical School, Hannover, Germany

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• Guntram Büsche,

  Affiliation Institute of Pathology, Hannover Medical School, Hannover, Germany

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• Christopher Baum,

  Affiliation Institute of Experimental Hematology; Hannover Medical School, Hannover, Germany

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• Ute Modlich

  * E-mail: Ute.modlich@pei.de

  Affiliations Research Group for Gene Modification in Stem Cells, LOEWE Center for Cell and Gene Therapy Frankfurt/Main and the Paul-Ehrlich-Institute, Langen, Germany, Institute of Experimental Hematology; Hannover Medical School, Hannover, Germany

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