The Effect of 5-Aminolevulinic Acid on Cytochrome P450-Mediated Prodrug Activation

Open Access

Peer-reviewed

Research Article

Mai Miura,

Affiliation Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259 B47 Nagatsuta-cho, Midori-ku, Yokohama, 226–8501, Japan
⨯
Kensuke Ito,

Affiliation Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259 B47 Nagatsuta-cho, Midori-ku, Yokohama, 226–8501, Japan
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Maiko Hayashi,

Affiliation Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259 B47 Nagatsuta-cho, Midori-ku, Yokohama, 226–8501, Japan
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Motowo Nakajima,

Affiliation SBI pharmaceuticals CO., LTD., Izumi Garden Tower 20F, 1-6-1, Roppongi, Minato-ku, Tokyo, 106–6020, Japan
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Tohru Tanaka,

Affiliation SBI pharmaceuticals CO., LTD., Izumi Garden Tower 20F, 1-6-1, Roppongi, Minato-ku, Tokyo, 106–6020, Japan
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Shun-ichiro Ogura

* E-mail: sogura@bio.titech.ac.jp

Affiliation Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259 B47 Nagatsuta-cho, Midori-ku, Yokohama, 226–8501, Japan
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Heme
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Cancer treatment
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Heme synthesis
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Gastric cancer
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Cytotoxicity
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Metabolites
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