Pleiotropic Effects of Bitter Taste Receptors on [Ca2+]i Mobilization, Hyperpolarization, and Relaxation of Human Airway Smooth Muscle Cells

Blanca Camoretti-Mercado; Susan H. Pauer; Hwan Mee Yong; Dan’elle C. Smith; Deepak A. Deshpande; Steven S. An; Stephen B. Liggett

doi:10.1371/journal.pone.0131582

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Research Article

Pleiotropic Effects of Bitter Taste Receptors on [Ca²⁺]_i Mobilization, Hyperpolarization, and Relaxation of Human Airway Smooth Muscle Cells

Blanca Camoretti-Mercado,

Affiliation Department of Medicine and the Center for Personalized Medicine and Genomics, University of South Florida Morsani College of Medicine, Tampa, FL, United States of America
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Susan H. Pauer,

Affiliation Department of Medicine and the Center for Personalized Medicine and Genomics, University of South Florida Morsani College of Medicine, Tampa, FL, United States of America
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Hwan Mee Yong,

Affiliation Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America
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Dan’elle C. Smith,

Affiliation Department of Medicine and the Center for Personalized Medicine and Genomics, University of South Florida Morsani College of Medicine, Tampa, FL, United States of America
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Deepak A. Deshpande,

Affiliation Department of Medicine and Center for Translational Medicine, Thomas Jefferson University, Philadelphia, PA, United States of America
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Steven S. An,

Affiliation Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America
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Stephen B. Liggett

* E-mail: sliggett@health.usf.edu

Affiliations Department of Medicine and the Center for Personalized Medicine and Genomics, University of South Florida Morsani College of Medicine, Tampa, FL, United States of America, Department of Molecular Pharmacology and Physiology, University of South Florida Morsani College of Medicine, Tampa, FL, United States of America
⨯

Pleiotropic Effects of Bitter Taste Receptors on [Ca²⁺]_i Mobilization, Hyperpolarization, and Relaxation of Human Airway Smooth Muscle Cells

Blanca Camoretti-Mercado,
Susan H. Pauer,
Hwan Mee Yong,
Dan’elle C. Smith,
Deepak A. Deshpande,
Steven S. An,
Stephen B. Liggett

Published: June 29, 2015
https://doi.org/10.1371/journal.pone.0131582

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Histamine
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