Curcumin Improves Amyloid β-Peptide (1-42) Induced Spatial Memory Deficits through BDNF-ERK Signaling Pathway

Lu Zhang; Yu Fang; Yuming Xu; Yajun Lian; Nanchang Xie; Tianwen Wu; Haifeng Zhang; Limin Sun; Ruifang Zhang; Zhenhua Wang

doi:10.1371/journal.pone.0131525

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Peer-reviewed

Research Article

Curcumin Improves Amyloid β-Peptide (1-42) Induced Spatial Memory Deficits through BDNF-ERK Signaling Pathway

Lu Zhang ,

Contributed equally to this work with: Lu Zhang, Yu Fang

Affiliations Key-Disciplines Laboratory Clinical-Medicine of Henan, Zhengzhou, Henan, PR China, Department of Neurology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, PR China
⨯
Yu Fang ,

Contributed equally to this work with: Lu Zhang, Yu Fang

* E-mail: Fang_Yuys@126.com

Affiliations Key-Disciplines Laboratory Clinical-Medicine of Henan, Zhengzhou, Henan, PR China, Department of Intensive Care Unit, First Affiliated Hospital, Zhengzhou University, Zhengzhou, Henan, PR China
⨯
Yuming Xu,

Affiliations Key-Disciplines Laboratory Clinical-Medicine of Henan, Zhengzhou, Henan, PR China, Department of Neurology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, PR China
⨯
Yajun Lian,

Affiliation Department of Neurology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, PR China
⨯
Nanchang Xie,

Affiliation Department of Neurology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, PR China
⨯
Tianwen Wu,

Affiliation Department of Neurology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, PR China
⨯
Haifeng Zhang,

Affiliation Department of Neurology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, PR China
⨯
Limin Sun,

Affiliation Department of Intensive Care Unit, First Affiliated Hospital, Zhengzhou University, Zhengzhou, Henan, PR China
⨯
Ruifang Zhang,

Affiliation Department of Intensive Care Unit, First Affiliated Hospital, Zhengzhou University, Zhengzhou, Henan, PR China
⨯
Zhenhua Wang

Affiliation Department of Intensive Care Unit, First Affiliated Hospital, Zhengzhou University, Zhengzhou, Henan, PR China
⨯

Curcumin Improves Amyloid β-Peptide (1-42) Induced Spatial Memory Deficits through BDNF-ERK Signaling Pathway

Lu Zhang,
Yu Fang,
Yuming Xu,
Yajun Lian,
Nanchang Xie,
Tianwen Wu,
Haifeng Zhang,
Limin Sun,
Ruifang Zhang,
Zhenhua Wang

Published: June 26, 2015
https://doi.org/10.1371/journal.pone.0131525

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