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Open Access

Peer-reviewed

Research Article

Phenformin Induces Cell Cycle Change, Apoptosis, and Mesenchymal-Epithelial Transition and Regulates the AMPK/mTOR/p70s6k and MAPK/ERK Pathways in Breast Cancer Cells

Zhao Liu,

Affiliation Department of Breast Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China
⨯
Lidong Ren,

Affiliation Department of Breast Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China
⨯
Chenghao Liu,

Affiliation Department of Breast Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China
⨯
Tiansong Xia,

Affiliation Department of Breast Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China
⨯
Xiaoming Zha ,

* E-mail: njzhaxm@qq.com (XZ); ws0801@hotmail.com (SW)

Affiliation Department of Breast Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China
⨯
Shui Wang

* E-mail: njzhaxm@qq.com (XZ); ws0801@hotmail.com (SW)

Affiliation Department of Breast Surgery, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China
⨯

Phenformin Induces Cell Cycle Change, Apoptosis, and Mesenchymal-Epithelial Transition and Regulates the AMPK/mTOR/p70s6k and MAPK/ERK Pathways in Breast Cancer Cells

Zhao Liu,
Lidong Ren,
Chenghao Liu,
Tiansong Xia,
Xiaoming Zha,
Shui Wang

x

Published: June 26, 2015
https://doi.org/10.1371/journal.pone.0131207

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Breast cancer
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Cancer treatment
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Apoptosis
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Metastasis
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Cell cycle and cell division
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Cyclins
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Mouse models
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Renal cancer
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