ABC Transporters and the Proteasome Complex Are Implicated in Susceptibility to Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis across Multiple Drugs

• Paola Nicoletti,

  Affiliation Department of Systems Biology, Columbia University, New York, New York, United States of America

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• Mukesh Bansal,

  Affiliation Department of Systems Biology, Columbia University, New York, New York, United States of America

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• Celine Lefebvre,

  Affiliations Department of Systems Biology, Columbia University, New York, New York, United States of America, INSERM U981, Institut Gustave Roussy, Villejuif, France

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• Paolo Guarnieri,

  Affiliations Department of Systems Biology, Columbia University, New York, New York, United States of America, Herbert Irving Comprehensive Cancer Center, Columbia University, New York, New York, United States of America

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• Yufeng Shen,

  Affiliations Department of Systems Biology, Columbia University, New York, New York, United States of America, Department of Biomedical Informatics, Columbia University, New York, New York, United States of America, JP Sulzberger Columbia Genome Center, Columbia University, New York, New York, United States of America

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• Itsik Pe’er,

  Affiliations Department of Systems Biology, Columbia University, New York, New York, United States of America, Department of Computer Science, Columbia University, New York, New York, United States of America

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• Andrea Califano ,

  * E-mail: ac2248@cumc.columbia.edu (AC); af2202@cumc.columbia.edu (AF)

  Affiliations Department of Systems Biology, Columbia University, New York, New York, United States of America, Herbert Irving Comprehensive Cancer Center, Columbia University, New York, New York, United States of America, Department of Biomedical Informatics, Columbia University, New York, New York, United States of America, Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, United States of America, Institute for Cancer Genetics, Columbia University, New York, NY 10032, United States of America

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• Aris Floratos

  * E-mail: ac2248@cumc.columbia.edu (AC); af2202@cumc.columbia.edu (AF)

  Affiliations Department of Systems Biology, Columbia University, New York, New York, United States of America, Department of Biomedical Informatics, Columbia University, New York, New York, United States of America

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