Immunization with a Recombinant, Pseudomonas fluorescens-Expressed, Mutant Form of Bacillus anthracis-Derived Protective Antigen Protects Rabbits from Anthrax Infection

Matthew D. Reed; Julie A. Wilder; William M. Mega; Julie A. Hutt; Philip J. Kuehl; Michelle W. Valderas; Lawrence L. Chew; Bertrand C. Liang; Charles H. Squires

doi:10.1371/journal.pone.0130952

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Open Access

Peer-reviewed

Research Article

Immunization with a Recombinant, Pseudomonas fluorescens-Expressed, Mutant Form of Bacillus anthracis-Derived Protective Antigen Protects Rabbits from Anthrax Infection

Matthew D. Reed,

Affiliation Lovelace Biomedical and Environmental Research Institute (LBERI), Preclinical Drug Development, 2425 Ridgecrest Drive SE, Albuquerque, New Mexico, United States of America
⨯
Julie A. Wilder,

Affiliation Lovelace Biomedical and Environmental Research Institute (LBERI), Preclinical Drug Development, 2425 Ridgecrest Drive SE, Albuquerque, New Mexico, United States of America
⨯
William M. Mega,

Affiliation Lovelace Biomedical and Environmental Research Institute (LBERI), Preclinical Drug Development, 2425 Ridgecrest Drive SE, Albuquerque, New Mexico, United States of America
⨯
Julie A. Hutt,

Affiliation Lovelace Biomedical and Environmental Research Institute (LBERI), Preclinical Drug Development, 2425 Ridgecrest Drive SE, Albuquerque, New Mexico, United States of America
⨯
Philip J. Kuehl,

Affiliation Lovelace Biomedical and Environmental Research Institute (LBERI), Preclinical Drug Development, 2425 Ridgecrest Drive SE, Albuquerque, New Mexico, United States of America
⨯
Michelle W. Valderas,

Current address: Southern Research Institute, 2000 Ninth Avenue South, Birmingham, AL, United States of America

Affiliation Lovelace Biomedical and Environmental Research Institute (LBERI), Preclinical Drug Development, 2425 Ridgecrest Drive SE, Albuquerque, New Mexico, United States of America
⨯
Lawrence L. Chew,

Current address: PaxVax Corporation, 3985A Sorrento Valley Boulevard, San Diego, United States of America

Affiliation Pfenex Inc., 10790 Roselle St., San Diego, California, United States of America
⨯
Bertrand C. Liang ,

* E-mail: bl@pfenex.com

Affiliation Pfenex Inc., 10790 Roselle St., San Diego, California, United States of America
⨯
Charles H. Squires

Current address: Leidos Life Sciences, 5202 Presidents Court, Frederick, MD, 21703, United States of America

Affiliation Pfenex Inc., 10790 Roselle St., San Diego, California, United States of America
⨯

Immunization with a Recombinant, Pseudomonas fluorescens-Expressed, Mutant Form of Bacillus anthracis-Derived Protective Antigen Protects Rabbits from Anthrax Infection

Matthew D. Reed,
Julie A. Wilder,
William M. Mega,
Julie A. Hutt,
Philip J. Kuehl,
Michelle W. Valderas,
Lawrence L. Chew,
Bertrand C. Liang,
Charles H. Squires

Published: July 24, 2015
https://doi.org/10.1371/journal.pone.0130952

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