Luteolin and Apigenin Attenuate 4-Hydroxy-2-Nonenal-Mediated Cell Death through Modulation of UPR, Nrf2-ARE and MAPK Pathways in PC12 Cells

Open Access

Peer-reviewed

Research Article

Pei-Shan Wu,

Affiliation Department of Biotechnology, Chia Nan University of Pharmacy and Science, Tainan, 717, Taiwan
⨯
Jui-Hung Yen,

Affiliation Department of Molecular Biology and Human Genetics, Tzu Chi University, Hualien, 970, Taiwan
⨯
Mei-Chun Kou,

Affiliation Department of Biotechnology, Chia Nan University of Pharmacy and Science, Tainan, 717, Taiwan
⨯
Ming-Jiuan Wu

* E-mail: imwu@mail.cnu.edu.tw

Affiliation Department of Biotechnology, Chia Nan University of Pharmacy and Science, Tainan, 717, Taiwan
⨯

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MAPK signaling cascades
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Endoplasmic reticulum
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Cytotoxicity
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Apoptosis
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Gene expression
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Stress signaling cascade
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Autophagic cell death
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Cellular stress responses
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