Chronic Replication Problems Impact Cell Morphology and Adhesion of DNA Ligase I Defective Cells

Paolo Cremaschi; Matteo Oliverio; Valentina Leva; Silvia Bione; Roberta Carriero; Giulia Mazzucco; Andrea Palamidessi; Giorgio Scita; Giuseppe Biamonti; Alessandra Montecucco

doi:10.1371/journal.pone.0130561

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Peer-reviewed

Research Article

Chronic Replication Problems Impact Cell Morphology and Adhesion of DNA Ligase I Defective Cells

Paolo Cremaschi ,

Contributed equally to this work with: Paolo Cremaschi, Matteo Oliverio

Affiliations Istituto di Genetica Molecolare, Consiglio Nazionale delle Ricerche (CNR), Pavia, Italy, Dipartimento di Biologia e Biotecnologie “L. Spallanzani”, Università degli Studi di Pavia, Pavia, Italy
⨯
Matteo Oliverio ,

Contributed equally to this work with: Paolo Cremaschi, Matteo Oliverio

Current address: Max-Plank-Institute for Metabolism Research, Cologne, Germany

Affiliation Istituto di Genetica Molecolare, Consiglio Nazionale delle Ricerche (CNR), Pavia, Italy
⨯
Valentina Leva,

Current address: Rottapharm SpA, Confienza (PV), Italy

Affiliation Istituto di Genetica Molecolare, Consiglio Nazionale delle Ricerche (CNR), Pavia, Italy
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Silvia Bione,

Affiliation Istituto di Genetica Molecolare, Consiglio Nazionale delle Ricerche (CNR), Pavia, Italy
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Roberta Carriero,

Affiliations Istituto di Genetica Molecolare, Consiglio Nazionale delle Ricerche (CNR), Pavia, Italy, Istituto Universitario di Studi Superiori (IUSS), Pavia, Italy
⨯
Giulia Mazzucco,

Affiliations Istituto di Genetica Molecolare, Consiglio Nazionale delle Ricerche (CNR), Pavia, Italy, Dipartimento di Biologia e Biotecnologie “L. Spallanzani”, Università degli Studi di Pavia, Pavia, Italy
⨯
Andrea Palamidessi,

Affiliation IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milano, Italy
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Giorgio Scita,

Affiliations IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milano, Italy, Dipartimento di Scienze della Salute, Università degli Studi di Milano, Milano, Italy
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Giuseppe Biamonti,

Affiliation Istituto di Genetica Molecolare, Consiglio Nazionale delle Ricerche (CNR), Pavia, Italy
⨯
Alessandra Montecucco

* E-mail: montecucco@igm.cnr.it

Affiliation Istituto di Genetica Molecolare, Consiglio Nazionale delle Ricerche (CNR), Pavia, Italy
⨯

Chronic Replication Problems Impact Cell Morphology and Adhesion of DNA Ligase I Defective Cells

Paolo Cremaschi,
Matteo Oliverio,
Valentina Leva,
Silvia Bione,
Roberta Carriero,
Giulia Mazzucco,
Andrea Palamidessi,
Giorgio Scita,
Giuseppe Biamonti,
Alessandra Montecucco

Published: July 7, 2015
https://doi.org/10.1371/journal.pone.0130561

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DNA damage
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Gene expression
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DNA replication
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