Tumor-Targeted Human T Cells Expressing CD28-Based Chimeric Antigen Receptors Circumvent CTLA-4 Inhibition

Open Access

Peer-reviewed

Research Article

Maud Condomines ,

* E-mail: condominesm@gmail.com (MC); m-sadelain@ski.mskcc.org (MS)

Affiliation Center for Cell Engineering and Molecular Pharmacology and Chemistry Program, Memorial Sloan-Kettering Cancer Center, New York, NY, 10065, United States of America
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Jon Arnason,

Affiliation Center for Cell Engineering and Molecular Pharmacology and Chemistry Program, Memorial Sloan-Kettering Cancer Center, New York, NY, 10065, United States of America
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Reuben Benjamin,

Affiliation Center for Cell Engineering and Molecular Pharmacology and Chemistry Program, Memorial Sloan-Kettering Cancer Center, New York, NY, 10065, United States of America
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Gertrude Gunset,

Affiliation Center for Cell Engineering and Molecular Pharmacology and Chemistry Program, Memorial Sloan-Kettering Cancer Center, New York, NY, 10065, United States of America
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Jason Plotkin,

Affiliation Center for Cell Engineering and Molecular Pharmacology and Chemistry Program, Memorial Sloan-Kettering Cancer Center, New York, NY, 10065, United States of America
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Michel Sadelain

* E-mail: condominesm@gmail.com (MC); m-sadelain@ski.mskcc.org (MS)

Affiliation Center for Cell Engineering and Molecular Pharmacology and Chemistry Program, Memorial Sloan-Kettering Cancer Center, New York, NY, 10065, United States of America
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T cells
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Cytotoxic T cells
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Cancer treatment
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Cancers and neoplasms
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Cytokines
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CD coreceptors
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Malignant tumors
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T cell receptors
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