CX3CR1 Is Expressed in Differentiated Human Ciliated Airway Cells and Co-Localizes with Respiratory Syncytial Virus on Cilia in a G Protein-Dependent Manner

Kwang-Il Jeong; Peter A. Piepenhagen; Michael Kishko; Joshua M. DiNapoli; Rachel P. Groppo; Linong Zhang; Jeffrey Almond; Harry Kleanthous; Simon Delagrave; Mark Parrington

doi:10.1371/journal.pone.0130517

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Open Access

Peer-reviewed

Research Article

CX3CR1 Is Expressed in Differentiated Human Ciliated Airway Cells and Co-Localizes with Respiratory Syncytial Virus on Cilia in a G Protein-Dependent Manner

Kwang-Il Jeong,

Affiliation Sanofi Pasteur, Research North America, 38 Sidney St., Cambridge, MA 02139, United States of America
⨯
Peter A. Piepenhagen,

Affiliation Genzyme, Department of Pathology, 5 The Mountain Rd., Framingham, MA 01701, United States of America
⨯
Michael Kishko,

Affiliation Sanofi Pasteur, Research North America, 38 Sidney St., Cambridge, MA 02139, United States of America
⨯
Joshua M. DiNapoli,

Affiliation Sanofi Pasteur, Research North America, 38 Sidney St., Cambridge, MA 02139, United States of America
⨯
Rachel P. Groppo,

Affiliation Sanofi Pasteur, Research North America, 38 Sidney St., Cambridge, MA 02139, United States of America
⨯
Linong Zhang,

Affiliation Sanofi Pasteur, Research North America, 38 Sidney St., Cambridge, MA 02139, United States of America
⨯
Jeffrey Almond,

Current address: University of Oxford, The Sir William Dunn School of Pathology, South Parks Road, Oxford, OX1 3RE, United Kingdom

Affiliation Sanofi Pasteur, Research North America, 38 Sidney St., Cambridge, MA 02139, United States of America
⨯
Harry Kleanthous,

Affiliation Sanofi Pasteur, Research North America, 38 Sidney St., Cambridge, MA 02139, United States of America
⨯
Simon Delagrave ,

* E-mail: simon.delagrave@sanofipasteur.com

Affiliation Sanofi Pasteur, Research North America, 38 Sidney St., Cambridge, MA 02139, United States of America
⨯
Mark Parrington

Affiliation Sanofi Pasteur, Research North America, 38 Sidney St., Cambridge, MA 02139, United States of America
⨯

CX3CR1 Is Expressed in Differentiated Human Ciliated Airway Cells and Co-Localizes with Respiratory Syncytial Virus on Cilia in a G Protein-Dependent Manner

Kwang-Il Jeong,
Peter A. Piepenhagen,
Michael Kishko,
Joshua M. DiNapoli,
Rachel P. Groppo,
Linong Zhang,
Jeffrey Almond,
Harry Kleanthous,
Simon Delagrave,
Mark Parrington

Published: June 24, 2015
https://doi.org/10.1371/journal.pone.0130517

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Cell differentiation
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Cilia
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Immunofluorescence
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Respiratory infections
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