Structure–Function Analysis of the Non-Muscle Myosin Light Chain Kinase (nmMLCK) Isoform by NMR Spectroscopy and Molecular Modeling: Influence of MYLK Variants

Kui Shen; Benjamin Ramirez; Brandon Mapes; Grace R. Shen; Vijay Gokhale; Mary E. Brown; Bernard Santarsiero; Yoshitaka Ishii; Steven M. Dudek; Ting Wang; Joe G. N. Garcia

doi:10.1371/journal.pone.0130515

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Peer-reviewed

Research Article

Structure–Function Analysis of the Non-Muscle Myosin Light Chain Kinase (nmMLCK) Isoform by NMR Spectroscopy and Molecular Modeling: Influence of MYLK Variants

Kui Shen,

Affiliation Institute for Personalized Respiratory Medicine, Section of Pulmonary, Critical Care, Sleep, and Allergy, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Benjamin Ramirez,

Affiliation Center for Structural Biology, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Brandon Mapes,

Affiliation Institute for Personalized Respiratory Medicine, Section of Pulmonary, Critical Care, Sleep, and Allergy, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Grace R. Shen,

Affiliation Institute for Personalized Respiratory Medicine, Section of Pulmonary, Critical Care, Sleep, and Allergy, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Vijay Gokhale,

Affiliation College of Pharmacy and BIO5 Institute, University of Arizona, Tucson, Arizona, United States of America
⨯
Mary E. Brown,

Affiliation Institute for Personalized Respiratory Medicine, Section of Pulmonary, Critical Care, Sleep, and Allergy, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Bernard Santarsiero,

Affiliation Center for Structural Biology, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Yoshitaka Ishii,

Affiliation Center for Structural Biology, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Steven M. Dudek,

Affiliation Institute for Personalized Respiratory Medicine, Section of Pulmonary, Critical Care, Sleep, and Allergy, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Ting Wang,

Affiliations Institute for Personalized Respiratory Medicine, Section of Pulmonary, Critical Care, Sleep, and Allergy, University of Illinois at Chicago, Chicago, Illinois, United States of America, Arizona Respiratory Center and Department of Medicine, University of Arizona, Tucson, Arizona, United States of America
⨯
Joe G. N. Garcia

* E-mail: skipgarcia@email.arizona.edu

Affiliations Institute for Personalized Respiratory Medicine, Section of Pulmonary, Critical Care, Sleep, and Allergy, University of Illinois at Chicago, Chicago, Illinois, United States of America, Arizona Respiratory Center and Department of Medicine, University of Arizona, Tucson, Arizona, United States of America
⨯

Structure–Function Analysis of the Non-Muscle Myosin Light Chain Kinase (nmMLCK) Isoform by NMR Spectroscopy and Molecular Modeling: Influence of MYLK Variants

Kui Shen,
Benjamin Ramirez,
Brandon Mapes,
Grace R. Shen,
Vijay Gokhale,
Mary E. Brown,
Bernard Santarsiero,
Yoshitaka Ishii,
Steven M. Dudek,
Ting Wang

Published: June 25, 2015
https://doi.org/10.1371/journal.pone.0130515

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