Homocysteine Induces Collagen I Expression by Downregulating Histone Methyltransferase G9a

Wenjing Lei; Yanjun Long; Shuang Li; Ze Liu; Fengxin Zhu; Fan Fan Hou; Jing Nie

doi:10.1371/journal.pone.0130421

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Peer-reviewed

Research Article

Homocysteine Induces Collagen I Expression by Downregulating Histone Methyltransferase G9a

Wenjing Lei,

Affiliation State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Division of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, P.R. China
⨯
Yanjun Long,

Affiliation State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Division of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, P.R. China
⨯
Shuang Li,

Affiliation State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Division of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, P.R. China
⨯
Ze Liu,

Affiliation State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Division of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, P.R. China
⨯
Fengxin Zhu,

Affiliation State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Division of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, P.R. China
⨯
Fan Fan Hou,

Affiliation State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Division of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, P.R. China
⨯
Jing Nie

* E-mail: niejing@smu.edu.cn

Affiliation State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Division of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, P.R. China
⨯

Homocysteine Induces Collagen I Expression by Downregulating Histone Methyltransferase G9a

Wenjing Lei,
Yanjun Long,
Shuang Li,
Ze Liu,
Fengxin Zhu,
Fan Fan Hou,
Jing Nie

Published: July 20, 2015
https://doi.org/10.1371/journal.pone.0130421

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Gene expression
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DNA methylation
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Collagens
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Small interfering RNA
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Transfection
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Fibrosis
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Histones
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Methionine
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