Improved Intraoperative Visualization of Nerves through a Myelin-Binding Fluorophore and Dual-Mode Laparoscopic Imaging

Victoria E. Cotero; Simon Y. Kimm; Tiberiu M. Siclovan; Rong Zhang; Evgenia M. Kim; Kazuhiro Matsumoto; Tatsuo Gondo; Peter T. Scardino; Siavash Yazdanfar; Vincent P. Laudone; Cristina A. Tan Hehir

doi:10.1371/journal.pone.0130276

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Open Access

Peer-reviewed

Research Article

Improved Intraoperative Visualization of Nerves through a Myelin-Binding Fluorophore and Dual-Mode Laparoscopic Imaging

Victoria E. Cotero,

Affiliation Diagnostics, Imaging and Biomedical Technologies, GE Global Research, Niskayuna, New York, United States of America
⨯
Simon Y. Kimm,

Affiliation Urology Service, Department of Surgery, Memorial Sloan—Kettering Cancer Center, New York, New York, United States of America
⨯
Tiberiu M. Siclovan,

Affiliation Diagnostics, Imaging and Biomedical Technologies, GE Global Research, Niskayuna, New York, United States of America
⨯
Rong Zhang,

Affiliation Diagnostics, Imaging and Biomedical Technologies, GE Global Research, Niskayuna, New York, United States of America
⨯
Evgenia M. Kim,

Affiliation Diagnostics, Imaging and Biomedical Technologies, GE Global Research, Niskayuna, New York, United States of America
⨯
Kazuhiro Matsumoto,

Affiliation Urology Service, Department of Surgery, Memorial Sloan—Kettering Cancer Center, New York, New York, United States of America
⨯
Tatsuo Gondo,

Affiliation Urology Service, Department of Surgery, Memorial Sloan—Kettering Cancer Center, New York, New York, United States of America
⨯
Peter T. Scardino,

Affiliation Urology Service, Department of Surgery, Memorial Sloan—Kettering Cancer Center, New York, New York, United States of America
⨯
Siavash Yazdanfar,

Affiliation Diagnostics, Imaging and Biomedical Technologies, GE Global Research, Niskayuna, New York, United States of America
⨯
Vincent P. Laudone,

Affiliation Urology Service, Department of Surgery, Memorial Sloan—Kettering Cancer Center, New York, New York, United States of America
⨯
Cristina A. Tan Hehir

* E-mail: tanhehir@ge.com

Affiliation Diagnostics, Imaging and Biomedical Technologies, GE Global Research, Niskayuna, New York, United States of America
⨯

Improved Intraoperative Visualization of Nerves through a Myelin-Binding Fluorophore and Dual-Mode Laparoscopic Imaging

Victoria E. Cotero,
Simon Y. Kimm,
Tiberiu M. Siclovan,
Rong Zhang,
Evgenia M. Kim,
Kazuhiro Matsumoto,
Tatsuo Gondo,
Peter T. Scardino,
Siavash Yazdanfar,
Vincent P. Laudone

Published: June 15, 2015
https://doi.org/10.1371/journal.pone.0130276

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