Evaluation of the Enterococcus faecalis Biofilm-Associated Virulence Factors AhrC and Eep in Rat Foreign Body Osteomyelitis and In Vitro Biofilm-Associated Antimicrobial Resistance

Kristi L. Frank; Paschalis Vergidis; Cassandra L. Brinkman; Kerryl E. Greenwood Quaintance; Aaron M. T. Barnes; Jayawant N. Mandrekar; Patrick M. Schlievert; Gary M. Dunny; Robin Patel

doi:10.1371/journal.pone.0130187

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Peer-reviewed

Research Article

Evaluation of the Enterococcus faecalis Biofilm-Associated Virulence Factors AhrC and Eep in Rat Foreign Body Osteomyelitis and In Vitro Biofilm-Associated Antimicrobial Resistance

Kristi L. Frank,

Affiliation Department of Microbiology, University of Minnesota, Minneapolis, Minnesota, United States of America
⨯
Paschalis Vergidis,

Current address: University of Pittsburgh, Division of Infectious Diseases, 3601 Fifth Avenue, Suite 3A, Falk Medical Building, Pittsburgh, Pennsylvania, United States of America

Affiliation Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Cassandra L. Brinkman,

Affiliation Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Kerryl E. Greenwood Quaintance,

Affiliation Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Aaron M. T. Barnes,

Affiliation Department of Microbiology, University of Minnesota, Minneapolis, Minnesota, United States of America
⨯
Jayawant N. Mandrekar,

Affiliation Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Patrick M. Schlievert,

Current address: Department of Microbiology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America

Affiliation Department of Microbiology, University of Minnesota, Minneapolis, Minnesota, United States of America
⨯
Gary M. Dunny,

Affiliation Department of Microbiology, University of Minnesota, Minneapolis, Minnesota, United States of America
⨯
Robin Patel

* E-mail: patel.robin@mayo.edu

Affiliations Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, United States of America, Division of Infectious Diseases, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, United States of America
⨯

Evaluation of the Enterococcus faecalis Biofilm-Associated Virulence Factors AhrC and Eep in Rat Foreign Body Osteomyelitis and In Vitro Biofilm-Associated Antimicrobial Resistance

Kristi L. Frank,
Paschalis Vergidis,
Cassandra L. Brinkman,
Kerryl E. Greenwood Quaintance,
Aaron M. T. Barnes,
Jayawant N. Mandrekar,
Patrick M. Schlievert,
Gary M. Dunny,
Robin Patel

Published: June 15, 2015
https://doi.org/10.1371/journal.pone.0130187

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Bacterial biofilms
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Enterococcus faecalis
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Osteomyelitis
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Enterococcus infections
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