Novel Broad Spectrum Inhibitors Targeting the Flavivirus Methyltransferase

Matthew Brecher; Hui Chen; Binbin Liu; Nilesh K. Banavali; Susan A. Jones; Jing Zhang; Zhong Li; Laura D. Kramer; Hongmin Li

doi:10.1371/journal.pone.0130062

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Open Access

Peer-reviewed

Research Article

Novel Broad Spectrum Inhibitors Targeting the Flavivirus Methyltransferase

Matthew Brecher ,

Contributed equally to this work with: Matthew Brecher, Hui Chen

Affiliation Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY, 12208 United States of America
⨯
Hui Chen ,

Contributed equally to this work with: Matthew Brecher, Hui Chen

Affiliation Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY, 12208 United States of America
⨯
Binbin Liu,

Affiliation Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY, 12208 United States of America
⨯
Nilesh K. Banavali,

Affiliations Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY, 12208 United States of America, Department of Biomedical Sciences, School of Public Health, State University of New York, Albany, PO Box 509, New York, 12201, United States of America
⨯
Susan A. Jones,

Affiliation Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY, 12208 United States of America
⨯
Jing Zhang,

Affiliation Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY, 12208 United States of America
⨯
Zhong Li,

Affiliation Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY, 12208 United States of America
⨯
Laura D. Kramer,

Affiliations Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY, 12208 United States of America, Department of Biomedical Sciences, School of Public Health, State University of New York, Albany, PO Box 509, New York, 12201, United States of America
⨯
Hongmin Li

* E-mail: Hongmin.li@health.ny.gov

Affiliations Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY, 12208 United States of America, Department of Biomedical Sciences, School of Public Health, State University of New York, Albany, PO Box 509, New York, 12201, United States of America
⨯

Novel Broad Spectrum Inhibitors Targeting the Flavivirus Methyltransferase

Matthew Brecher,
Hui Chen,
Binbin Liu,
Nilesh K. Banavali,
Susan A. Jones,
Jing Zhang,
Zhong Li,
Laura D. Kramer,
Hongmin Li

Published: June 22, 2015
https://doi.org/10.1371/journal.pone.0130062

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Methylation
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