Palmitate Inhibits SIRT1-Dependent BMAL1/CLOCK Interaction and Disrupts Circadian Gene Oscillations in Hepatocytes

Open Access

Peer-reviewed

Research Article

Xin Tong,

Affiliation Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
⨯
Deqiang Zhang,

Affiliation Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
⨯
Blake Arthurs,

Affiliation Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
⨯
Pei Li,

Affiliation Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
⨯
Leigh Durudogan,

Affiliation Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
⨯
Neil Gupta,

Affiliation Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
⨯
Lei Yin

* E-mail: leiyin@umich.edu

Affiliation Department of Molecular & Integrative Physiology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
⨯

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Hepatocytes
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Circadian oscillators
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Circadian rhythms
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Genetic oscillators
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Protein interactions
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Drug interactions
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Immunoprecipitation
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Transfection
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