Defining the Human Brain Proteome Using Transcriptomics and Antibody-Based Profiling with a Focus on the Cerebral Cortex

Evelina Sjöstedt; Linn Fagerberg; Björn M. Hallström; Anna Häggmark; Nicholas Mitsios; Peter Nilsson; Fredrik Pontén; Tomas Hökfelt; Mathias Uhlén; Jan Mulder

doi:10.1371/journal.pone.0130028

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Open Access

Peer-reviewed

Research Article

Defining the Human Brain Proteome Using Transcriptomics and Antibody-Based Profiling with a Focus on the Cerebral Cortex

Evelina Sjöstedt,

Affiliations Science for Life Laboratory, School of Biotechnology, KTH-Royal Institute of Technology, Stockholm, Sweden, Science for Life Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden
⨯
Linn Fagerberg,

Affiliation Science for Life Laboratory, School of Biotechnology, KTH-Royal Institute of Technology, Stockholm, Sweden
⨯
Björn M. Hallström,

Affiliation Science for Life Laboratory, School of Biotechnology, KTH-Royal Institute of Technology, Stockholm, Sweden
⨯
Anna Häggmark,

Affiliation Science for Life Laboratory, School of Biotechnology, KTH-Royal Institute of Technology, Stockholm, Sweden
⨯
Nicholas Mitsios,

Affiliation Science for Life Laboratory, Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
⨯
Peter Nilsson,

Affiliation Science for Life Laboratory, School of Biotechnology, KTH-Royal Institute of Technology, Stockholm, Sweden
⨯
Fredrik Pontén,

Affiliation Science for Life Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden
⨯
Tomas Hökfelt,

Affiliation Science for Life Laboratory, Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
⨯
Mathias Uhlén,

Affiliation Science for Life Laboratory, School of Biotechnology, KTH-Royal Institute of Technology, Stockholm, Sweden
⨯
Jan Mulder

* E-mail: jan.mulder@ki.se

Affiliation Science for Life Laboratory, Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
⨯

Defining the Human Brain Proteome Using Transcriptomics and Antibody-Based Profiling with a Focus on the Cerebral Cortex

Evelina Sjöstedt,
Linn Fagerberg,
Björn M. Hallström,
Anna Häggmark,
Nicholas Mitsios,
Peter Nilsson,
Fredrik Pontén,
Tomas Hökfelt,
Mathias Uhlén,
Jan Mulder

Published: June 15, 2015
https://doi.org/10.1371/journal.pone.0130028

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Gene expression
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Long non-coding RNA
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Neurons
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Immunohistochemistry techniques
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Frontal lobe
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Transcriptome analysis
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Astrocytes
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Protein expression
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