Computational Modelling of NF-κB Activation by IL-1RI and Its Co-Receptor TILRR, Predicts a Role for Cytoskeletal Sequestration of IκBα in Inflammatory Signalling

Open Access

Peer-reviewed

Research Article

David M. Rhodes ,

Contributed equally to this work with: David M. Rhodes, Sarah A. Smith

Affiliations Department of Cardiovascular Science, Medical School, University of Sheffield, United Kingdom, Department of Computer Science, University of Sheffield, Sheffield, United Kingdom
⨯
Sarah A. Smith ,

Contributed equally to this work with: David M. Rhodes, Sarah A. Smith

Affiliation Department of Cardiovascular Science, Medical School, University of Sheffield, United Kingdom
⨯
Mike Holcombe,

Affiliation Department of Computer Science, University of Sheffield, Sheffield, United Kingdom
⨯
Eva E. Qwarnstrom

* E-mail: e.qwarnstrom@sheffield.ac.uk

Affiliation Department of Cardiovascular Science, Medical School, University of Sheffield, United Kingdom
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Cytoskeleton
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Cytoplasm
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Biochemical simulations
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Inflammation
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Actins
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