Innate Response Activator (IRA) B Cells Reside in Human Tonsils and Internalize Bacteria In Vitro

Nico Chiappini; Rocco Cantisani; Laura Pancotto; Paolo Ruggiero; Domenico Rosa; Andrea Manetti; Antonio Romano; Francesca Montagnani; Sylvie Bertholet; Flora Castellino; Giuseppe Del Giudice

doi:10.1371/journal.pone.0129879

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Open Access

Peer-reviewed

Research Article

Innate Response Activator (IRA) B Cells Reside in Human Tonsils and Internalize Bacteria In Vitro

Nico Chiappini ,

Contributed equally to this work with: Nico Chiappini, Rocco Cantisani

* E-mail: nico.x.chiappini@gsk.com (NC); rocco.x.cantisani@gsk.com (RC)

Affiliation Novartis Vaccines and Diagnostics (a GSK company), Research Center, Via Fiorentina 1, Siena, Italy
⨯
Rocco Cantisani ,

Contributed equally to this work with: Nico Chiappini, Rocco Cantisani

* E-mail: nico.x.chiappini@gsk.com (NC); rocco.x.cantisani@gsk.com (RC)

Affiliation Novartis Vaccines and Diagnostics (a GSK company), Research Center, Via Fiorentina 1, Siena, Italy
⨯
Laura Pancotto,

Affiliation Novartis Vaccines and Diagnostics (a GSK company), Research Center, Via Fiorentina 1, Siena, Italy
⨯
Paolo Ruggiero,

Affiliation Novartis Vaccines and Diagnostics (a GSK company), Research Center, Via Fiorentina 1, Siena, Italy
⨯
Domenico Rosa,

Affiliation Novartis Vaccines and Diagnostics (a GSK company), Research Center, Via Fiorentina 1, Siena, Italy
⨯
Andrea Manetti,

Affiliation Novartis Vaccines and Diagnostics (a GSK company), Research Center, Via Fiorentina 1, Siena, Italy
⨯
Antonio Romano,

Affiliation Otorhinolaryngology Department, University Hospital Le Scotte, Strada delle Scotte 14, Siena, Italy
⨯
Francesca Montagnani,

Affiliation Department of Medical Biotechnologies, Infectious Unit, University Hospital Le Scotte, Strada delle Scotte 14, Siena, Italy
⨯
Sylvie Bertholet,

Affiliation Novartis Vaccines and Diagnostics (a GSK company), Research Center, Via Fiorentina 1, Siena, Italy
⨯
Flora Castellino,

Current address: Center for Human Immunology, NHLBI, NIH, Rockville Pike, Bethesda, Maryland, United States of America

Affiliation Novartis Vaccines and Diagnostics (a GSK company), Research Center, Via Fiorentina 1, Siena, Italy
⨯
Giuseppe Del Giudice

Affiliation Novartis Vaccines and Diagnostics (a GSK company), Research Center, Via Fiorentina 1, Siena, Italy
⨯

Innate Response Activator (IRA) B Cells Reside in Human Tonsils and Internalize Bacteria In Vitro

Nico Chiappini,
Rocco Cantisani,
Laura Pancotto,
Paolo Ruggiero,
Domenico Rosa,
Andrea Manetti,
Antonio Romano,
Francesca Montagnani,
Sylvie Bertholet,
Flora Castellino

Published: June 12, 2015
https://doi.org/10.1371/journal.pone.0129879

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