Mitogen-Inducible Gene-6 Mediates Feedback Inhibition from Mutated BRAF towards the Epidermal Growth Factor Receptor and Thereby Limits Malignant Transformation

• Malgorzata Milewska,

  Affiliation Systems Biology Ireland, University College Dublin, Dublin, Ireland

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• David Romano,

  Affiliation Systems Biology Ireland, University College Dublin, Dublin, Ireland

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• Ana Herrero,

  Affiliation Systems Biology Ireland, University College Dublin, Dublin, Ireland

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• Maria Luisa Guerriero,

  Affiliation Systems Biology Ireland, University College Dublin, Dublin, Ireland

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• Marc Birtwistle,

  Affiliation Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

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• Franz Quehenberger,

  Affiliation Institute of Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria

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• Stefan Hatzl,

  Affiliation Division of Hematology, Medical University of Graz, Graz, Austria

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• Boris N. Kholodenko,

  Affiliations Systems Biology Ireland, University College Dublin, Dublin, Ireland, Conway Institute of Biomolecular & Biomedical Research, University College Dublin, Dublin, Ireland, School of Medicine and Medical Science, University College Dublin, Dublin, Ireland

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• Oreste Segatto,

  Affiliation Laboratory of Immunology, Regina Elena Cancer Institute, Rome, Italy

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• Walter Kolch,

  Affiliations Systems Biology Ireland, University College Dublin, Dublin, Ireland, Conway Institute of Biomolecular & Biomedical Research, University College Dublin, Dublin, Ireland, School of Medicine and Medical Science, University College Dublin, Dublin, Ireland

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• Armin Zebisch

  * E-mail: armin.zebisch@medunigraz.at

  Affiliation Division of Hematology, Medical University of Graz, Graz, Austria

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