Avoiding the Enumeration of Infeasible Elementary Flux Modes by Including Transcriptional Regulatory Rules in the Enumeration Process Saves Computational Costs

Open Access

Peer-reviewed

Research Article

Christian Jungreuthmayer ,

* E-mail: christian.jungreuthmayer@acib.at (CJ); juergen.zanghellini@acib.at (JZ)

Affiliations Austrian Centre of Industrial Biotechnology, Vienna, Austria, EU, Department of Biotechnology, University of Natural Resources and Life Sciences, Vienna, Austria, EU
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David E. Ruckerbauer,

Affiliations Austrian Centre of Industrial Biotechnology, Vienna, Austria, EU, Department of Biotechnology, University of Natural Resources and Life Sciences, Vienna, Austria, EU
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Matthias P. Gerstl,

Affiliations Austrian Centre of Industrial Biotechnology, Vienna, Austria, EU, Department of Biotechnology, University of Natural Resources and Life Sciences, Vienna, Austria, EU
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Michael Hanscho,

Affiliations Austrian Centre of Industrial Biotechnology, Vienna, Austria, EU, Department of Biotechnology, University of Natural Resources and Life Sciences, Vienna, Austria, EU
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Jürgen Zanghellini

* E-mail: christian.jungreuthmayer@acib.at (CJ); juergen.zanghellini@acib.at (JZ)

Affiliations Austrian Centre of Industrial Biotechnology, Vienna, Austria, EU, Department of Biotechnology, University of Natural Resources and Life Sciences, Vienna, Austria, EU
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Gene regulation
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Metabolic networks
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Transcriptional control
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Stoichiometry
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Genetic networks
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Glucose
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Gene regulatory networks
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Mitochondria
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