IFN-Gamma Inhibits JC Virus Replication in Glial Cells by Suppressing T-Antigen Expression

Francesca Isabella De-Simone; Rahsan Sariyer; Yolanda-Lopez Otalora; Shadan Yarandi; Michael Craigie; Jennifer Gordon; Ilker Kudret Sariyer

doi:10.1371/journal.pone.0129694

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Peer-reviewed

Research Article

IFN-Gamma Inhibits JC Virus Replication in Glial Cells by Suppressing T-Antigen Expression

Francesca Isabella De-Simone,

Affiliation Department of Neuroscience, Center for Neurovirology, Temple University School of Medicine, 3500 North Broad Street, 7th Floor, Philadelphia, PA, 19140, United States of America
⨯
Rahsan Sariyer,

Affiliation Department of Neuroscience, Center for Neurovirology, Temple University School of Medicine, 3500 North Broad Street, 7th Floor, Philadelphia, PA, 19140, United States of America
⨯
Yolanda-Lopez Otalora,

Affiliation Department of Neuroscience, Center for Neurovirology, Temple University School of Medicine, 3500 North Broad Street, 7th Floor, Philadelphia, PA, 19140, United States of America
⨯
Shadan Yarandi,

Affiliation Department of Neuroscience, Center for Neurovirology, Temple University School of Medicine, 3500 North Broad Street, 7th Floor, Philadelphia, PA, 19140, United States of America
⨯
Michael Craigie,

Affiliation Department of Neuroscience, Center for Neurovirology, Temple University School of Medicine, 3500 North Broad Street, 7th Floor, Philadelphia, PA, 19140, United States of America
⨯
Jennifer Gordon,

Affiliation Department of Neuroscience, Center for Neurovirology, Temple University School of Medicine, 3500 North Broad Street, 7th Floor, Philadelphia, PA, 19140, United States of America
⨯
Ilker Kudret Sariyer

* E-mail: isariyer@temple.edu

Affiliation Department of Neuroscience, Center for Neurovirology, Temple University School of Medicine, 3500 North Broad Street, 7th Floor, Philadelphia, PA, 19140, United States of America
⨯

IFN-Gamma Inhibits JC Virus Replication in Glial Cells by Suppressing T-Antigen Expression

Francesca Isabella De-Simone,
Rahsan Sariyer,
Yolanda-Lopez Otalora,
Shadan Yarandi,
Michael Craigie,
Jennifer Gordon,
Ilker Kudret Sariyer

Published: June 10, 2015
https://doi.org/10.1371/journal.pone.0129694

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Viral replication
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Immune suppression
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Transfection
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DNA replication
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Plasmid construction
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JC virus
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