Polychlorinated Biphenyls Induce Mitochondrial Dysfunction in SH-SY5Y Neuroblastoma Cells

Stefania Cocco; Agnese Secondo; Adelaide Del Viscovo; Claudio Procaccini; Luigi Formisano; Cristina Franco; Alba Esposito; Antonella Scorziello; Giuseppe Matarese; Gianfranco Di Renzo; Lorella Maria Teresa Canzoniero

doi:10.1371/journal.pone.0129481

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Peer-reviewed

Research Article

Polychlorinated Biphenyls Induce Mitochondrial Dysfunction in SH-SY5Y Neuroblastoma Cells

Stefania Cocco,

Affiliation Division of Pharmacology, Dept. of Neuroscience and Reproductive and Odontostomatological Sciences, School of Medicine, “Federico II” University of Naples, Via Sergio Pansini 5, Naples, 80131, Italy
⨯
Agnese Secondo,

Affiliation Division of Pharmacology, Dept. of Neuroscience and Reproductive and Odontostomatological Sciences, School of Medicine, “Federico II” University of Naples, Via Sergio Pansini 5, Naples, 80131, Italy
⨯
Adelaide Del Viscovo,

Affiliation Dept. of Science and Technology-DST, University of Sannio, via Port'Arsa 11, 82100 Benevento, Italy
⨯
Claudio Procaccini,

Affiliation Laboratorio di Immunologia, Istituto di Endocrinologia e Oncologia Sperimentale, Consiglio Nazionale delle Ricerche (IEOS-CNR), c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli “Federico II”, Napoli, Italy
⨯
Luigi Formisano,

Affiliation Dept. of Science and Technology-DST, University of Sannio, via Port'Arsa 11, 82100 Benevento, Italy
⨯
Cristina Franco,

Affiliation Division of Pharmacology, Dept. of Neuroscience and Reproductive and Odontostomatological Sciences, School of Medicine, “Federico II” University of Naples, Via Sergio Pansini 5, Naples, 80131, Italy
⨯
Alba Esposito,

Affiliation Division of Pharmacology, Dept. of Neuroscience and Reproductive and Odontostomatological Sciences, School of Medicine, “Federico II” University of Naples, Via Sergio Pansini 5, Naples, 80131, Italy
⨯
Antonella Scorziello,

Affiliation Division of Pharmacology, Dept. of Neuroscience and Reproductive and Odontostomatological Sciences, School of Medicine, “Federico II” University of Naples, Via Sergio Pansini 5, Naples, 80131, Italy
⨯
Giuseppe Matarese,

Affiliations Dipartimento di Medicina e Chirurgia, Università di Salerno, Baronissi Campus, Baronissi, Salerno, Italy, IRCCS MultiMedica, Milano, Italy
⨯
Gianfranco Di Renzo,

Affiliation Division of Pharmacology, Dept. of Neuroscience and Reproductive and Odontostomatological Sciences, School of Medicine, “Federico II” University of Naples, Via Sergio Pansini 5, Naples, 80131, Italy
⨯
Lorella Maria Teresa Canzoniero

* E-mail: canzoniero@unisannio.it

Affiliation Dept. of Science and Technology-DST, University of Sannio, via Port'Arsa 11, 82100 Benevento, Italy
⨯

Polychlorinated Biphenyls Induce Mitochondrial Dysfunction in SH-SY5Y Neuroblastoma Cells

Stefania Cocco,
Agnese Secondo,
Adelaide Del Viscovo,
Claudio Procaccini,
Luigi Formisano,
Cristina Franco,
Alba Esposito,
Antonella Scorziello,
Giuseppe Matarese,
Gianfranco Di Renzo

Published: June 23, 2015
https://doi.org/10.1371/journal.pone.0129481

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Mitochondria
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Pyruvic acid
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Nitric oxide
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Oxidative phosphorylation
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Neuroblastoma cells
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