Characterizing the DNA Damage Response by Cell Tracking Algorithms and Cell Features Classification Using High-Content Time-Lapse Analysis

Open Access

Peer-reviewed

Research Article

Walter Georgescu,

Affiliation Lawrence Berkeley National Laboratory, Life Sciences Division, Berkeley, CA, United States of America
⨯
Alma Osseiran,

Affiliation Lawrence Berkeley National Laboratory, Life Sciences Division, Berkeley, CA, United States of America
⨯
Maria Rojec,

Affiliation Lawrence Berkeley National Laboratory, Life Sciences Division, Berkeley, CA, United States of America
⨯
Yueyong Liu,

Affiliation Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02215, United States of America
⨯
Maxime Bombrun,

Affiliation CNRS, UMR 6158, LIMOS, F-63173, Aubiere, France
⨯
Jonathan Tang,

Affiliation Lawrence Berkeley National Laboratory, Life Sciences Division, Berkeley, CA, United States of America
⨯
Sylvain V. Costes

* E-mail: svcostes@lbl.gov

Affiliation Lawrence Berkeley National Laboratory, Life Sciences Division, Berkeley, CA, United States of America
⨯

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DNA repair
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Ionizing radiation
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Cell death
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DNA damage
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Epithelial cells
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Image processing
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Linear programming
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Radiobiology
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