Yeast Assay Highlights the Intrinsic Genomic Instability of Human PML Intron 6 over Intron 3 and the Role of Replication Fork Proteins

Roland Chanet; Guy Kienda; Amélie Heneman-Masurel; Laurence Vernis; Bruno Cassinat; Philippe Guardiola; Pierre Fenaux; Christine Chomienne; Meng-Er Huang

doi:10.1371/journal.pone.0129222

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Peer-reviewed

Research Article

Yeast Assay Highlights the Intrinsic Genomic Instability of Human PML Intron 6 over Intron 3 and the Role of Replication Fork Proteins

Roland Chanet,

Affiliations UMR3348 “Genotoxic Stress and Cancer”, Centre National de la Recherche Scientifique, Orsay, France, Institut Curie, Centre de Recherche, Orsay, France
⨯
Guy Kienda,

Affiliations UMR3348 “Genotoxic Stress and Cancer”, Centre National de la Recherche Scientifique, Orsay, France, Institut Curie, Centre de Recherche, Orsay, France
⨯
Amélie Heneman-Masurel,

Affiliations UMR3348 “Genotoxic Stress and Cancer”, Centre National de la Recherche Scientifique, Orsay, France, Institut Curie, Centre de Recherche, Orsay, France
⨯
Laurence Vernis,

Affiliations UMR3348 “Genotoxic Stress and Cancer”, Centre National de la Recherche Scientifique, Orsay, France, Institut Curie, Centre de Recherche, Orsay, France
⨯
Bruno Cassinat,

Affiliations AP-HP, Hôpital Saint-Louis, Paris, France, Inserm UMRS-1131, Hôpital Saint-Louis, Université Paris Diderot, Paris, France
⨯
Philippe Guardiola,

Affiliation Plateforme SNP, Transcriptome & Epigénomique, Centre Hospitalier Universitaire, Angers, France
⨯
Pierre Fenaux,

Affiliations AP-HP, Hôpital Saint-Louis, Paris, France, Inserm UMRS-1131, Hôpital Saint-Louis, Université Paris Diderot, Paris, France
⨯
Christine Chomienne,

Affiliations AP-HP, Hôpital Saint-Louis, Paris, France, Inserm UMRS-1131, Hôpital Saint-Louis, Université Paris Diderot, Paris, France
⨯
Meng-Er Huang

* E-mail: meng-er.huang@curie.fr

Affiliations UMR3348 “Genotoxic Stress and Cancer”, Centre National de la Recherche Scientifique, Orsay, France, Institut Curie, Centre de Recherche, Orsay, France
⨯

Yeast Assay Highlights the Intrinsic Genomic Instability of Human PML Intron 6 over Intron 3 and the Role of Replication Fork Proteins

Roland Chanet,
Guy Kienda,
Amélie Heneman-Masurel,
Laurence Vernis,
Bruno Cassinat,
Philippe Guardiola,
Pierre Fenaux,
Christine Chomienne,
Meng-Er Huang

Published: June 8, 2015
https://doi.org/10.1371/journal.pone.0129222

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Introns
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Yeast
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