Designing and Testing of Novel Taxanes to Probe the Highly Complex Mechanisms by Which Taxanes Bind to Microtubules and Cause Cytotoxicity to Cancer Cells

• Marc St. George,

  Affiliation Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada

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• Ahmed T. Ayoub,

  Affiliation Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada

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• Asok Banerjee,

  Affiliation Department of Biochemistry, University of Texas Health Science Center, San Antonio, Texas, United States of America

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• Cassandra D. M. Churchill,

  Affiliation Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada

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• Philip Winter,

  Affiliation Department of Oncology, University of Alberta, Edmonton, Alberta, Canada

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• Mariusz Klobukowski,

  Affiliation Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada

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• Carol E. Cass,

  Affiliation Department of Oncology, University of Alberta, Edmonton, Alberta, Canada

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• Richard F. Ludueña,

  Affiliation Department of Biochemistry, University of Texas Health Science Center, San Antonio, Texas, United States of America

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• Jack A. Tuszynski ,

  * E-mail: jackt@ualberta.ca (JAT); sambasivarao.damaraju@ualberta.ca (SD)

  Affiliations Department of Oncology, University of Alberta, Edmonton, Alberta, Canada, Department of Physics, University of Alberta, Edmonton, Alberta, Canada

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• Sambasivarao Damaraju

  * E-mail: jackt@ualberta.ca (JAT); sambasivarao.damaraju@ualberta.ca (SD)

  Affiliation Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada

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