Identification of Influenza A/PR/8/34 Donor Viruses Imparting High Hemagglutinin Yields to Candidate Vaccine Viruses in Eggs

Adam Johnson; Li-Mei Chen; Emily Winne; Wanda Santana; Maureen G. Metcalfe; Guaniri Mateu-Petit; Callie Ridenour; M. Jaber Hossain; Julie Villanueva; Sherif R. Zaki; Tracie L. Williams; Nancy J. Cox; John R. Barr; Ruben O. Donis

doi:10.1371/journal.pone.0128982

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Open Access

Peer-reviewed

Research Article

Identification of Influenza A/PR/8/34 Donor Viruses Imparting High Hemagglutinin Yields to Candidate Vaccine Viruses in Eggs

Adam Johnson ,

Contributed equally to this work with: Adam Johnson, Li-Mei Chen

Affiliation Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Li-Mei Chen ,

Contributed equally to this work with: Adam Johnson, Li-Mei Chen

* E-mail: rvd6@cdc.gov (ROD); bpr5@cdc.gov (LMC)

Affiliation Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Emily Winne,

Affiliation Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Wanda Santana,

Affiliation Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Maureen G. Metcalfe,

Affiliation National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Guaniri Mateu-Petit,

Affiliation Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Callie Ridenour,

Affiliation Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
M. Jaber Hossain,

Affiliation Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Julie Villanueva,

Affiliation Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Sherif R. Zaki,

Affiliation National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Tracie L. Williams,

Affiliation Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Nancy J. Cox,

Affiliation Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
John R. Barr,

Affiliation Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Ruben O. Donis

* E-mail: rvd6@cdc.gov (ROD); bpr5@cdc.gov (LMC)

Affiliation Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯

Identification of Influenza A/PR/8/34 Donor Viruses Imparting High Hemagglutinin Yields to Candidate Vaccine Viruses in Eggs

Adam Johnson,
Li-Mei Chen,
Emily Winne,
Wanda Santana,
Maureen G. Metcalfe,
Guaniri Mateu-Petit,
Callie Ridenour,
M. Jaber Hossain,
Julie Villanueva,
Sherif R. Zaki

Published: June 11, 2015
https://doi.org/10.1371/journal.pone.0128982

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