Amino Acid Substitutions Improve the Immunogenicity of H7N7HA Protein and Protect Mice against Lethal H7N7 Viral Challenge

Open Access

Peer-reviewed

Research Article

Subaschandrabose Rajesh kumar ,

Contributed equally to this work with: Subaschandrabose Rajesh kumar, Mookkan Prabakaran

Affiliation Animal Health Biotechnology, Temasek Lifesciences Laboratory, 1 Research Link, National University of Singapore, Singapore, Republic of Singapore
⨯
Mookkan Prabakaran ,

Contributed equally to this work with: Subaschandrabose Rajesh kumar, Mookkan Prabakaran

Affiliation Animal Health Biotechnology, Temasek Lifesciences Laboratory, 1 Research Link, National University of Singapore, Singapore, Republic of Singapore
⨯
Kattur Venkatachalam Ashok raj,

Affiliation Animal Health Biotechnology, Temasek Lifesciences Laboratory, 1 Research Link, National University of Singapore, Singapore, Republic of Singapore
⨯
Fang He,

Affiliation Animal Health Biotechnology, Temasek Lifesciences Laboratory, 1 Research Link, National University of Singapore, Singapore, Republic of Singapore
⨯
Jimmy Kwang

* E-mail: kwang@tll.org.sg

Affiliations Animal Health Biotechnology, Temasek Lifesciences Laboratory, 1 Research Link, National University of Singapore, Singapore, Republic of Singapore, Department of Microbiology, Faculty of Medicine, National University of Singapore, Singapore, Republic of Singapore
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Viral vaccines
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H7N9
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Amino acid substitution
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T cells
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Antibodies
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Antigens
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Mouse models
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