Systemic siRNA Nanoparticle-Based Drugs Combined with Radiofrequency Ablation for Cancer Therapy

Muneeb Ahmed; Gaurav Kumar; Gemma Navarro; Yuanguo Wang; Svetlana Gourevitch; Marwan H. Moussa; Nir Rozenblum; Tatyana Levchenko; Eithan Galun; Vladimir P. Torchilin; S. Nahum Goldberg

doi:10.1371/journal.pone.0128910

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Open Access

Peer-reviewed

Research Article

Systemic siRNA Nanoparticle-Based Drugs Combined with Radiofrequency Ablation for Cancer Therapy

Muneeb Ahmed ,

* E-mail: mahmed@bidmc.harvard.edu

Affiliation Laboratory for Minimally Invasive Tumor Therapies, Department of Radiology, Beth Israel Deaconess Medical Center/Harvard Medical School, 1 Deaconess Rd.–WCC-308B, Boston, Massachusetts, 02215, United States of America
⨯
Gaurav Kumar,

Affiliation Laboratory for Minimally Invasive Tumor Therapies, Department of Radiology, Beth Israel Deaconess Medical Center/Harvard Medical School, 1 Deaconess Rd.–WCC-308B, Boston, Massachusetts, 02215, United States of America
⨯
Gemma Navarro,

Affiliation Department of Pharmaceutical Sciences and Center for Pharmaceutical Biotechnology and Nanomedicine, Northeastern University, 140 The Fenway, Boston, Massachusetts, 02115, United States of America
⨯
Yuanguo Wang,

Affiliation Laboratory for Minimally Invasive Tumor Therapies, Department of Radiology, Beth Israel Deaconess Medical Center/Harvard Medical School, 1 Deaconess Rd.–WCC-308B, Boston, Massachusetts, 02215, United States of America
⨯
Svetlana Gourevitch,

Affiliation The Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Medical Center, Kiryat Hadassah POB 12000, Jerusalem, 91120, Israel
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Marwan H. Moussa,

Affiliation Laboratory for Minimally Invasive Tumor Therapies, Department of Radiology, Beth Israel Deaconess Medical Center/Harvard Medical School, 1 Deaconess Rd.–WCC-308B, Boston, Massachusetts, 02215, United States of America
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Nir Rozenblum,

Affiliation The Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Medical Center, Kiryat Hadassah POB 12000, Jerusalem, 91120, Israel
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Tatyana Levchenko,

Affiliation Department of Pharmaceutical Sciences and Center for Pharmaceutical Biotechnology and Nanomedicine, Northeastern University, 140 The Fenway, Boston, Massachusetts, 02115, United States of America
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Eithan Galun,

Affiliation The Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Medical Center, Kiryat Hadassah POB 12000, Jerusalem, 91120, Israel
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Vladimir P. Torchilin,

Affiliation Department of Pharmaceutical Sciences and Center for Pharmaceutical Biotechnology and Nanomedicine, Northeastern University, 140 The Fenway, Boston, Massachusetts, 02115, United States of America
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S. Nahum Goldberg

Affiliations Laboratory for Minimally Invasive Tumor Therapies, Department of Radiology, Beth Israel Deaconess Medical Center/Harvard Medical School, 1 Deaconess Rd.–WCC-308B, Boston, Massachusetts, 02215, United States of America, Division of Image-guided Therapy and Interventional Oncology, Department of Radiology, Hadassah Hebrew University Medical Center, Kiryat Hadassah POB 12000, Jerusalem, 91120, Israel
⨯

Systemic siRNA Nanoparticle-Based Drugs Combined with Radiofrequency Ablation for Cancer Therapy

Muneeb Ahmed,
Gaurav Kumar,
Gemma Navarro,
Yuanguo Wang,
Svetlana Gourevitch,
Marwan H. Moussa,
Nir Rozenblum,
Tatyana Levchenko,
Eithan Galun,
Vladimir P. Torchilin

Published: July 8, 2015
https://doi.org/10.1371/journal.pone.0128910

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