Conditional Deletion of TAK1 in T Cells Reveals a Pivotal Role of TCRαβ+ Intraepithelial Lymphocytes in Preventing Lymphopenia-Associated Colitis

Open Access

Peer-reviewed

Research Article

Conditional Deletion of TAK1 in T Cells Reveals a Pivotal Role of TCRαβ⁺ Intraepithelial Lymphocytes in Preventing Lymphopenia-Associated Colitis

Hideki Sanjo ,

* E-mail: hsanjo@shinshu-u.ac.jp

Affiliation Department of Molecular and Cellular Immunology, Shinshu University School of Medicine, Nagano, Japan
⨯
Shigeo Tokumaru,

Affiliation Department of Molecular and Cellular Immunology, Shinshu University School of Medicine, Nagano, Japan
⨯
Shizuo Akira,

Affiliation Laboratory of Host Defense, Immunology Frontier Research Center, Osaka University, Osaka, Japan
⨯
Shinsuke Taki

Affiliation Department of Molecular and Cellular Immunology, Shinshu University School of Medicine, Nagano, Japan
⨯

T cells
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Mouse models
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Colitis
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Flow cytometry
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Regulatory T cells
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Colon
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Cytokines
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Gastrointestinal tract
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