RNA Interference-Guided Targeting of Hepatitis C Virus Replication with Antisense Locked Nucleic Acid-Based Oligonucleotides Containing 8-oxo-dG Modifications

• Margit Mutso ,

  ¶‡ These authors are joint first authors on this work.

  Affiliations Institute of Technology, University of Tartu, Tartu, Estonia, GeneCode, Ltd., Tallinn, Estonia

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• Andrei Nikonov ,

  ¶‡ These authors are joint first authors on this work.

  Affiliations Institute of Technology, University of Tartu, Tartu, Estonia, GeneCode, Ltd., Tallinn, Estonia

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• Arno Pihlak ,

  ¶‡ These authors are joint first authors on this work.

  Affiliation GeneCode, Ltd., Tallinn, Estonia

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• Eva Žusinaite,

  Affiliations Institute of Technology, University of Tartu, Tartu, Estonia, GeneCode, Ltd., Tallinn, Estonia

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• Liane Viru,

  Affiliations Institute of Technology, University of Tartu, Tartu, Estonia, GeneCode, Ltd., Tallinn, Estonia

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• Anastasia Selyutina,

  Affiliation Institute of Technology, University of Tartu, Tartu, Estonia

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• Tõnu Reintamm,

  Affiliations GeneCode, Ltd., Tallinn, Estonia, Department of Gene Technology, Tallinn University of Technology, Tallinn, Estonia

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• Merike Kelve,

  Affiliations GeneCode, Ltd., Tallinn, Estonia, Department of Gene Technology, Tallinn University of Technology, Tallinn, Estonia

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• Mart Saarma,

  Affiliation Institute of Biotechnology, University of Helsinki, Helsinki, Finland

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• Mati Karelson,

  Affiliations GeneCode, Ltd., Tallinn, Estonia, Institute of Chemistry, University of Tartu, Tartu, Estonia

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• Andres Merits

  * E-mail: andres.merits@ut.ee

  Affiliation Institute of Technology, University of Tartu, Tartu, Estonia

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