Selective Blockade of Interferon-α and -β Reveals Their Non-Redundant Functions in a Mouse Model of West Nile Virus Infection

Open Access

Peer-reviewed

Research Article

Kathleen C. F. Sheehan,

Affiliations Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America, Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, Missouri, United States of America
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Helen M. Lazear,

Affiliation Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America
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Michael S. Diamond,

Affiliations Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, United States of America, Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, Missouri, United States of America
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Robert D. Schreiber

* E-mail: Schreiber@immunology.wustl.edu

Affiliations Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America, Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, Missouri, United States of America
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West Nile virus
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Interferons
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Enzyme-linked immunoassays
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Mouse models
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Antiviral therapy
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Phosphorylation
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Hamsters
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Hybridomas
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